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Table 3 Analysis of risk factor profile for MPNs according to JAK2 V617F mutation

From: The epidemiology and clinical characteristics of myeloproliferative neoplasms in Malaysia

Risk factors JAK2 V617F OR (95% CI) p-value
Positive
n (%)
Negative
n (%)
Previous thrombosis 183 (28.6) 29 (13.2) 2.624 (1.717, 4.009) < 0.001
Old age (≥ 60 years) 258 (40.1) 63 (28.1) 1.691 (1.215, 2.354) 0.002
Sex: male 327 (50.8) 123 (55.4) 0.830 (0.611, 1.127) 0.234
Hypertension 327 (50.9) 83 (38.1) 1.688 (1.234, 2.310) 0.001
Dyslipidemia 212 (33.0) 59 (27.2) 1.320 (0.939, 1.855) 0.110
Diabetes 97 (15.1) 39 (17.9) 0.818 (0.545, 1.229) 0.335
Smoking 129 (20.1) 46 (21.1) 0.944 (0.648, 1.376) 0.765
Obese 33 (5.1) 19 (8.8) 0.566 (0.316, 1.011) 0.054