Table 3 Analysis of risk factor profile for MPNs according to JAK2 V617F mutation
From: The epidemiology and clinical characteristics of myeloproliferative neoplasms in Malaysia
Risk factors | JAK2 V617F | OR (95% CI) | p-value | |
|---|---|---|---|---|
Positive n (%) | Negative n (%) | |||
Previous thrombosis | 183 (28.6) | 29 (13.2) | 2.624 (1.717, 4.009) | < 0.001 |
Old age (≥ 60 years) | 258 (40.1) | 63 (28.1) | 1.691 (1.215, 2.354) | 0.002 |
Sex: male | 327 (50.8) | 123 (55.4) | 0.830 (0.611, 1.127) | 0.234 |
Hypertension | 327 (50.9) | 83 (38.1) | 1.688 (1.234, 2.310) | 0.001 |
Dyslipidemia | 212 (33.0) | 59 (27.2) | 1.320 (0.939, 1.855) | 0.110 |
Diabetes | 97 (15.1) | 39 (17.9) | 0.818 (0.545, 1.229) | 0.335 |
Smoking | 129 (20.1) | 46 (21.1) | 0.944 (0.648, 1.376) | 0.765 |
Obese | 33 (5.1) | 19 (8.8) | 0.566 (0.316, 1.011) | 0.054 |