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Fig. 3 | Experimental Hematology & Oncology

Fig. 3

From: Methylome of human senescent hematopoietic progenitors

Fig. 3

Characterization of the differentially methylated regions in senescent HSPCs. a Mapping of hypo- and hyperDMRs to chromatin states of CD34+ cells. Hypomethlation is spread diversely throughout different regions of the genome, with promoter and enhancer regions showing a propensity for hypomethylation. b Motif enrichment analysis of statistically significantly DMRs shows high concordance of both hypermethylated and hypomethylated regions of the genome, with selected targets noted. Hypomethylated regions show a clustering of CEBP enhancer regions

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