Fig. 2
From: Methylome of human senescent hematopoietic progenitors
Whole genome bisulfite sequencing of senescent HSPCs. Focal loss of DNA methylation observed in senescent HSPCs obtained through whole genome bisulfite sequencing. Senescent population (CD34+ SA-β-Gal –) is represented in orange, with non-senescent population (CD34+ SA-β-Gal +) shown in blue. This shows alterations in methylation along a representative segment of chromosome 6, with focal hypomethylation of gene promoter regions of HLA-DRB5 and HLA-DRB6