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Fig. 2 | Experimental Hematology & Oncology

Fig. 2

From: Methylome of human senescent hematopoietic progenitors

Fig. 2

Whole genome bisulfite sequencing of senescent HSPCs. Focal loss of DNA methylation observed in senescent HSPCs obtained through whole genome bisulfite sequencing. Senescent population (CD34+ SA-β-Gal –) is represented in orange, with non-senescent population (CD34+ SA-β-Gal +) shown in blue. This shows alterations in methylation along a representative segment of chromosome 6, with focal hypomethylation of gene promoter regions of HLA-DRB5 and HLA-DRB6

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