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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: Early vs. late MRD response- and risk-based treatment intensification of childhood acute lymphoblastic leukemia: a prospective pilot study from Saudi Arabia

Fig. 5

Outcomes by cytogenetic type and subgroup, B-cell phenotype. The 5-year overall survival by genetic subtype (a) and subgroup (c), and the 5-year event-free survival by genetic subtype (b) and subgroup (d) are shown. The overall survival and event-free survival of the t(1;19) cytogenetic abnormality and the MLL-rearrangement (MLLR) clustered distinctly away from all other genetic subtypes (a, b). Patients with the t(1;19) and MLLR subgroup had significantly (p < 0.05) inferior survival outcomes compared to all other genetic subtypes (c, d)

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