TY - JOUR AU - Schumacher, T. N. AU - Schreiber, R. D. PY - 2015 DA - 2015// TI - Neoantigens in cancer immunotherapy JO - Science VL - 348 UR - https://doi.org/10.1126/science.aaa4971 DO - 10.1126/science.aaa4971 ID - Schumacher2015 ER - TY - JOUR AU - Yu, S. AU - Li, A. AU - Liu, Q. AU - Li, T. AU - Yuan, X. AU - Han, X. PY - 2017 DA - 2017// TI - Chimeric antigen receptor T cells: a novel therapy for solid tumors JO - J Hematol Oncol. VL - 10 UR - https://doi.org/10.1186/s13045-017-0444-9 DO - 10.1186/s13045-017-0444-9 ID - Yu2017 ER - TY - JOUR AU - Yu, S. AU - Li, A. AU - Liu, Q. AU - Yuan, X. AU - Xu, H. AU - Jiao, D. PY - 2017 DA - 2017// TI - Recent advances of bispecific antibodies in solid tumors JO - J Hematol Oncol. VL - 10 UR - https://doi.org/10.1186/s13045-017-0522-z DO - 10.1186/s13045-017-0522-z ID - Yu2017 ER - TY - JOUR AU - Hailemichael, Y. AU - Woods, A. AU - Fu, T. AU - He, Q. AU - Nielsen, M. C. AU - Hasan, F. PY - 2018 DA - 2018// TI - Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy JO - J Clin Invest. VL - 128 UR - https://doi.org/10.1172/JCI93303 DO - 10.1172/JCI93303 ID - Hailemichael2018 ER - TY - JOUR AU - Yi, M. AU - Jiao, D. AU - Xu, H. AU - Liu, Q. AU - Zhao, W. AU - Han, X. PY - 2018 DA - 2018// TI - Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors JO - Mol Cancer. VL - 17 UR - https://doi.org/10.1186/s12943-018-0864-3 DO - 10.1186/s12943-018-0864-3 ID - Yi2018 ER - TY - JOUR AU - Chen, D. S. AU - Mellman, I. PY - 2013 DA - 2013// TI - Oncology meets immunology: the cancer-immunity cycle JO - Immunity VL - 39 UR - https://doi.org/10.1016/j.immuni.2013.07.012 DO - 10.1016/j.immuni.2013.07.012 ID - Chen2013 ER - TY - JOUR AU - Liu, D. AU - Wang, S. AU - Bindeman, W. PY - 2017 DA - 2017// TI - Clinical applications of PD-L1 bioassays for cancer immunotherapy JO - J Hematol Oncol. VL - 10 UR - https://doi.org/10.1186/s13045-017-0479-y DO - 10.1186/s13045-017-0479-y ID - Liu2017 ER - TY - JOUR AU - Neefjes, J. AU - Jongsma, M. L. AU - Paul, P. AU - Bakke, O. PY - 2011 DA - 2011// TI - Towards a systems understanding of MHC class I and MHC class II antigen presentation JO - Nat Rev Immunol VL - 11 UR - https://doi.org/10.1038/nri3084 DO - 10.1038/nri3084 ID - Neefjes2011 ER - TY - JOUR AU - Hellmann, M. D. AU - Callahan, M. K. AU - Awad, M. M. AU - Calvo, E. AU - Ascierto, P. A. AU - Atmaca, A. PY - 2018 DA - 2018// TI - Tumor mutational burden and efficacy of nivolumab monotherapy and in combination with ipilimumab in small-cell lung cancer JO - Cancer Cell VL - 33 ID - Hellmann2018 ER - TY - JOUR AU - Goodman, A. M. AU - Kato, S. AU - Bazhenova, L. AU - Patel, S. P. AU - Frampton, G. M. AU - Miller, V. PY - 2017 DA - 2017// TI - Tumor mutational burden as an independent predictor of response to immunotherapy in diverse cancers JO - Mol Cancer Ther VL - 16 UR - https://doi.org/10.1158/1535-7163.MCT-17-0386 DO - 10.1158/1535-7163.MCT-17-0386 ID - Goodman2017 ER - TY - JOUR AU - Rooney, M. S. AU - Shukla, S. A. AU - Wu, C. J. AU - Getz, G. AU - Hacohen, N. PY - 2015 DA - 2015// TI - Molecular and genetic properties of tumors associated with local immune cytolytic activity JO - Cell VL - 160 UR - https://doi.org/10.1016/j.cell.2014.12.033 DO - 10.1016/j.cell.2014.12.033 ID - Rooney2015 ER - TY - JOUR AU - Gong, J. AU - Chehrazi-Raffle, A. AU - Reddi, S. AU - Salgia, R. PY - 2018 DA - 2018// TI - Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations JO - J Immunother Cancer. VL - 6 UR - https://doi.org/10.1186/s40425-018-0316-z DO - 10.1186/s40425-018-0316-z ID - Gong2018 ER - TY - JOUR AU - Turajlic, S. AU - Litchfield, K. AU - Xu, H. AU - Rosenthal, R. AU - McGranahan, N. AU - Reading, J. L. PY - 2017 DA - 2017// TI - Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis JO - Lancet Oncol. VL - 18 UR - https://doi.org/10.1016/S1470-2045(17)30516-8 DO - 10.1016/S1470-2045(17)30516-8 ID - Turajlic2017 ER - TY - JOUR AU - Rizvi, N. A. AU - Hellmann, M. D. AU - Snyder, A. AU - Kvistborg, P. AU - Makarov, V. AU - Havel, J. J. PY - 2015 DA - 2015// TI - Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer JO - Science VL - 348 UR - https://doi.org/10.1126/science.aaa1348 DO - 10.1126/science.aaa1348 ID - Rizvi2015 ER - TY - JOUR AU - Le, D. T. AU - Durham, J. N. AU - Smith, K. N. AU - Wang, H. AU - Bartlett, B. R. AU - Aulakh, L. K. PY - 2017 DA - 2017// TI - Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade JO - Science VL - 357 UR - https://doi.org/10.1126/science.aan6733 DO - 10.1126/science.aan6733 ID - Le2017 ER - TY - JOUR AU - Carbone, D. P. AU - Reck, M. AU - Paz-Ares, L. AU - Creelan, B. AU - Horn, L. AU - Steins, M. PY - 2017 DA - 2017// TI - First-line nivolumab in stage IV or recurrent non-small-cell lung cancer JO - N Engl J Med VL - 376 UR - https://doi.org/10.1056/NEJMoa1613493 DO - 10.1056/NEJMoa1613493 ID - Carbone2017 ER - TY - JOUR AU - Li, G. M. PY - 2008 DA - 2008// TI - Mechanisms and functions of DNA mismatch repair JO - Cell Res VL - 18 UR - https://doi.org/10.1038/cr.2007.115 DO - 10.1038/cr.2007.115 ID - Li2008 ER - TY - JOUR AU - Overman, M. J. AU - McDermott, R. AU - Leach, J. L. AU - Lonardi, S. AU - Lenz, H. J. AU - Morse, M. A. PY - 2017 DA - 2017// TI - Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study JO - Lancet Oncol. VL - 18 UR - https://doi.org/10.1016/S1470-2045(17)30422-9 DO - 10.1016/S1470-2045(17)30422-9 ID - Overman2017 ER - TY - JOUR AU - Kim, S. T. AU - Cristescu, R. AU - Bass, A. J. AU - Kim, K. M. AU - Odegaard, J. I. AU - Kim, K. PY - 2018 DA - 2018// TI - Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer JO - Nat Med VL - 24 UR - https://doi.org/10.1038/s41591-018-0101-z DO - 10.1038/s41591-018-0101-z ID - Kim2018 ER - TY - JOUR AU - Janjigian, Y. Y. AU - Sanchez-Vega, F. AU - Jonsson, P. AU - Chatila, W. K. AU - Hechtman, J. F. AU - Ku, G. Y. PY - 2018 DA - 2018// TI - Genetic predictors of response to systemic therapy in esophagogastric cancer JO - Cancer Discov VL - 8 UR - https://doi.org/10.1158/2159-8290.CD-17-0787 DO - 10.1158/2159-8290.CD-17-0787 ID - Janjigian2018 ER - TY - JOUR AU - Anagnostou, V. AU - Smith, K. N. AU - Forde, P. M. AU - Niknafs, N. AU - Bhattacharya, R. AU - White, J. PY - 2017 DA - 2017// TI - Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer JO - Cancer Discov VL - 7 UR - https://doi.org/10.1158/2159-8290.CD-16-0828 DO - 10.1158/2159-8290.CD-16-0828 ID - Anagnostou2017 ER - TY - JOUR AU - Long, J. AU - Lin, J. AU - Wang, A. AU - Wu, L. AU - Zheng, Y. AU - Yang, X. PY - 2017 DA - 2017// TI - PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy JO - J Hematol Oncol. VL - 10 UR - https://doi.org/10.1186/s13045-017-0511-2 DO - 10.1186/s13045-017-0511-2 ID - Long2017 ER - TY - JOUR AU - Snyder, A. AU - Makarov, V. AU - Merghoub, T. AU - Yuan, J. AU - Zaretsky, J. M. AU - Desrichard, A. PY - 2014 DA - 2014// TI - Genetic basis for clinical response to CTLA-4 blockade in melanoma JO - N Engl J Med VL - 371 UR - https://doi.org/10.1056/NEJMoa1406498 DO - 10.1056/NEJMoa1406498 ID - Snyder2014 ER - TY - JOUR AU - Routy, B. AU - Chatelier, E. AU - Derosa, L. AU - Duong, C. P. M. AU - Alou, M. T. AU - Daillere, R. PY - 2018 DA - 2018// TI - Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors JO - Science VL - 359 UR - https://doi.org/10.1126/science.aan3706 DO - 10.1126/science.aan3706 ID - Routy2018 ER - TY - JOUR AU - Matson, V. AU - Fessler, J. AU - Bao, R. AU - Chongsuwat, T. AU - Zha, Y. AU - Alegre, M. L. PY - 2018 DA - 2018// TI - The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients JO - Science VL - 359 UR - https://doi.org/10.1126/science.aao3290 DO - 10.1126/science.aao3290 ID - Matson2018 ER - TY - JOUR AU - Gopalakrishnan, V. AU - Spencer, C. N. AU - Nezi, L. AU - Reuben, A. AU - Andrews, M. C. AU - Karpinets, T. V. PY - 2018 DA - 2018// TI - Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients JO - Science VL - 359 UR - https://doi.org/10.1126/science.aan4236 DO - 10.1126/science.aan4236 ID - Gopalakrishnan2018 ER - TY - JOUR AU - Yi, M. AU - Yu, S. AU - Qin, S. AU - Liu, Q. AU - Xu, H. AU - Zhao, W. PY - 2018 DA - 2018// TI - Gut microbiome modulates efficacy of immune checkpoint inhibitors JO - J Hematol Oncol. VL - 11 UR - https://doi.org/10.1186/s13045-018-0592-6 DO - 10.1186/s13045-018-0592-6 ID - Yi2018 ER - TY - JOUR AU - Hackl, H. AU - Charoentong, P. AU - Finotello, F. AU - Trajanoski, Z. PY - 2016 DA - 2016// TI - Computational genomics tools for dissecting tumour-immune cell interactions JO - Nat Rev Genet VL - 17 UR - https://doi.org/10.1038/nrg.2016.67 DO - 10.1038/nrg.2016.67 ID - Hackl2016 ER - TY - JOUR AU - Snyder, A. AU - Chan, T. A. PY - 2015 DA - 2015// TI - Immunogenic peptide discovery in cancer genomes JO - Curr Opin Genet Dev VL - 30 UR - https://doi.org/10.1016/j.gde.2014.12.003 DO - 10.1016/j.gde.2014.12.003 ID - Snyder2015 ER - TY - JOUR AU - Ding, L. AU - Wendl, M. C. AU - McMichael, J. F. AU - Raphael, B. J. PY - 2014 DA - 2014// TI - Expanding the computational toolbox for mining cancer genomes JO - Nat Rev Genet VL - 15 UR - https://doi.org/10.1038/nrg3767 DO - 10.1038/nrg3767 ID - Ding2014 ER - TY - JOUR AU - Pabinger, S. AU - Dander, A. AU - Fischer, M. AU - Snajder, R. AU - Sperk, M. AU - Efremova, M. PY - 2014 DA - 2014// TI - A survey of tools for variant analysis of next-generation genome sequencing data JO - Brief Bioinform VL - 15 UR - https://doi.org/10.1093/bib/bbs086 DO - 10.1093/bib/bbs086 ID - Pabinger2014 ER - TY - JOUR AU - Warren, R. L. AU - Choe, G. AU - Freeman, D. J. AU - Castellarin, M. AU - Munro, S. AU - Moore, R. PY - 2012 DA - 2012// TI - Derivation of HLA types from shotgun sequence datasets JO - Genome Med. VL - 4 UR - https://doi.org/10.1186/gm396 DO - 10.1186/gm396 ID - Warren2012 ER - TY - JOUR AU - Szolek, A. AU - Schubert, B. AU - Mohr, C. AU - Sturm, M. AU - Feldhahn, M. AU - Kohlbacher, O. PY - 2014 DA - 2014// TI - OptiType: precision HLA typing from next-generation sequencing data JO - Bioinformatics VL - 30 UR - https://doi.org/10.1093/bioinformatics/btu548 DO - 10.1093/bioinformatics/btu548 ID - Szolek2014 ER - TY - JOUR AU - Nariai, N. AU - Kojima, K. AU - Saito, S. AU - Mimori, T. AU - Sato, Y. AU - Kawai, Y. PY - 2015 DA - 2015// TI - HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data JO - BMC Genomics. VL - 16 UR - https://doi.org/10.1186/1471-2164-16-S2-S7 DO - 10.1186/1471-2164-16-S2-S7 ID - Nariai2015 ER - TY - JOUR AU - Huang, Y. AU - Yang, J. AU - Ying, D. AU - Zhang, Y. AU - Shotelersuk, V. AU - Hirankarn, N. PY - 2015 DA - 2015// TI - HLAreporter: a tool for HLA typing from next generation sequencing data JO - Genome Med. VL - 7 UR - https://doi.org/10.1186/s13073-015-0145-3 DO - 10.1186/s13073-015-0145-3 ID - Huang2015 ER - TY - JOUR AU - Kim, S. AU - Kim, H. S. AU - Kim, E. AU - Lee, M. G. AU - Shin, E. C. AU - Paik, S. PY - 2018 DA - 2018// TI - Neopepsee: accurate genome-level prediction of neoantigens by harnessing sequence and amino acid immunogenicity information JO - Ann Oncol VL - 29 ID - Kim2018 ER - TY - JOUR AU - Hoof, I. AU - Peters, B. AU - Sidney, J. AU - Pedersen, L. E. AU - Sette, A. AU - Lund, O. PY - 2009 DA - 2009// TI - NetMHCpan, a method for MHC class I binding prediction beyond humans JO - Immunogenetics VL - 61 UR - https://doi.org/10.1007/s00251-008-0341-z DO - 10.1007/s00251-008-0341-z ID - Hoof2009 ER - TY - JOUR AU - Stambrook, P. J. AU - Maher, J. AU - Farzaneh, F. PY - 2017 DA - 2017// TI - Cancer immunotherapy: whence and whither JO - Mol Cancer Res VL - 15 UR - https://doi.org/10.1158/1541-7786.MCR-16-0427 DO - 10.1158/1541-7786.MCR-16-0427 ID - Stambrook2017 ER - TY - JOUR AU - Rock, K. L. AU - Reits, E. AU - Neefjes, J. PY - 2016 DA - 2016// TI - Present yourself! By MHC class I and MHC class II molecules JO - Trends Immunol VL - 37 UR - https://doi.org/10.1016/j.it.2016.08.010 DO - 10.1016/j.it.2016.08.010 ID - Rock2016 ER - TY - JOUR AU - Josephs, T. M. AU - Grant, E. J. AU - Gras, S. PY - 2017 DA - 2017// TI - Molecular challenges imposed by MHC-I restricted long epitopes on T cell immunity JO - Biol Chem VL - 398 UR - https://doi.org/10.1515/hsz-2016-0305 DO - 10.1515/hsz-2016-0305 ID - Josephs2017 ER - TY - JOUR AU - Karosiene, E. AU - Lundegaard, C. AU - Lund, O. AU - Nielsen, M. PY - 2012 DA - 2012// TI - NetMHCcons: a consensus method for the major histocompatibility complex class I predictions JO - Immunogenetics VL - 64 UR - https://doi.org/10.1007/s00251-011-0579-8 DO - 10.1007/s00251-011-0579-8 ID - Karosiene2012 ER - TY - JOUR AU - Andreatta, M. AU - Karosiene, E. AU - Rasmussen, M. AU - Stryhn, A. AU - Buus, S. AU - Nielsen, M. PY - 2015 DA - 2015// TI - Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification JO - Immunogenetics VL - 67 UR - https://doi.org/10.1007/s00251-015-0873-y DO - 10.1007/s00251-015-0873-y ID - Andreatta2015 ER - TY - JOUR AU - Bomberger, J. M. AU - Ely, K. H. AU - Bangia, N. AU - Ye, S. AU - Green, K. A. AU - Green, W. R. PY - 2014 DA - 2014// TI - Pseudomonas aeruginosa Cif protein enhances the ubiquitination and proteasomal degradation of the transporter associated with antigen processing (TAP) and reduces major histocompatibility complex (MHC) class I antigen presentation JO - J Biol Chem VL - 289 UR - https://doi.org/10.1074/jbc.M113.459271 DO - 10.1074/jbc.M113.459271 ID - Bomberger2014 ER - TY - JOUR AU - Nielsen, M. AU - Lundegaard, C. AU - Lund, O. AU - Kesmir, C. PY - 2005 DA - 2005// TI - The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage JO - Immunogenetics VL - 57 UR - https://doi.org/10.1007/s00251-005-0781-7 DO - 10.1007/s00251-005-0781-7 ID - Nielsen2005 ER - TY - JOUR AU - Zhang, G. L. AU - Petrovsky, N. AU - Kwoh, C. K. AU - August, J. T. AU - Brusic, V. PY - 2006 DA - 2006// TI - PRED(TAP): a system for prediction of peptide binding to the human transporter associated with antigen processing JO - Immunome Res. VL - 2 UR - https://doi.org/10.1186/1745-7580-2-3 DO - 10.1186/1745-7580-2-3 ID - Zhang2006 ER - TY - JOUR AU - Trolle, T. AU - Nielsen, M. PY - 2014 DA - 2014// TI - NetTepi: an integrated method for the prediction of T cell epitopes JO - Immunogenetics VL - 66 UR - https://doi.org/10.1007/s00251-014-0779-0 DO - 10.1007/s00251-014-0779-0 ID - Trolle2014 ER - TY - JOUR AU - Lee, C. H. AU - Yelensky, R. AU - Jooss, K. AU - Chan, T. A. PY - 2018 DA - 2018// TI - Update on tumor neoantigens and their utility: why it is good to be different JO - Trends Immunol VL - 39 UR - https://doi.org/10.1016/j.it.2018.04.005 DO - 10.1016/j.it.2018.04.005 ID - Lee2018 ER - TY - JOUR AU - Kaufman, H. L. AU - Kohlhapp, F. J. AU - Zloza, A. PY - 2015 DA - 2015// TI - Oncolytic viruses: a new class of immunotherapy drugs JO - Nat Rev Drug Discov. VL - 14 UR - https://doi.org/10.1038/nrd4663 DO - 10.1038/nrd4663 ID - Kaufman2015 ER - TY - JOUR AU - Marelli, G. AU - Howells, A. AU - Lemoine, N. R. AU - Wang, Y. PY - 2018 DA - 2018// TI - Oncolytic viral therapy and the immune system: a double-edged sword against cancer JO - Front Immunol. VL - 9 UR - https://doi.org/10.3389/fimmu.2018.00866 DO - 10.3389/fimmu.2018.00866 ID - Marelli2018 ER - TY - JOUR AU - Parato, K. A. AU - Breitbach, C. J. AU - Boeuf, F. AU - Wang, J. AU - Storbeck, C. AU - Ilkow, C. PY - 2012 DA - 2012// TI - The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers JO - Mol Ther VL - 20 UR - https://doi.org/10.1038/mt.2011.276 DO - 10.1038/mt.2011.276 ID - Parato2012 ER - TY - JOUR AU - Yin, J. AU - Markert, J. M. AU - Leavenworth, J. W. PY - 2017 DA - 2017// TI - Modulation of the intratumoral immune landscape by oncolytic herpes simplex virus virotherapy JO - Front Oncol. VL - 7 UR - https://doi.org/10.3389/fonc.2017.00136 DO - 10.3389/fonc.2017.00136 ID - Yin2017 ER - TY - JOUR AU - Woller, N. AU - Gurlevik, E. AU - Fleischmann-Mundt, B. AU - Schumacher, A. AU - Knocke, S. AU - Kloos, A. M. PY - 2015 DA - 2015// TI - Viral infection of tumors overcomes resistance to PD-1-immunotherapy by broadening neoantigenome-directed T-cell responses JO - Mol Ther VL - 23 UR - https://doi.org/10.1038/mt.2015.115 DO - 10.1038/mt.2015.115 ID - Woller2015 ER - TY - JOUR AU - Chen, C. Y. AU - Hutzen, B. AU - Wedekind, M. F. AU - Cripe, T. P. PY - 2018 DA - 2018// TI - Oncolytic virus and PD-1/PD-L1 blockade combination therapy JO - Oncolytic Virother. VL - 7 UR - https://doi.org/10.2147/OV.S145532 DO - 10.2147/OV.S145532 ID - Chen2018 ER - TY - JOUR AU - Bartee, E. AU - Li, Z. PY - 2017 DA - 2017// TI - In vivo and in situ programming of tumor immunity by combining oncolytics and PD-1 immune checkpoint blockade JO - Exp Hematol Oncol. VL - 6 UR - https://doi.org/10.1186/s40164-017-0075-4 DO - 10.1186/s40164-017-0075-4 ID - Bartee2017 ER - TY - JOUR AU - Tremblay-LeMay, R. AU - Rastgoo, N. AU - Chang, H. PY - 2018 DA - 2018// TI - Modulating PD-L1 expression in multiple myeloma: an alternative strategy to target the PD-1/PD-L1 pathway JO - J Hematol Oncol. VL - 11 UR - https://doi.org/10.1186/s13045-018-0589-1 DO - 10.1186/s13045-018-0589-1 ID - Tremblay-LeMay2018 ER - TY - JOUR AU - Zamarin, D. AU - Ricca, J. M. AU - Sadekova, S. AU - Oseledchyk, A. AU - Yu, Y. AU - Blumenschein, W. M. PY - 2018 DA - 2018// TI - PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy JO - J Clin Invest. VL - 128 UR - https://doi.org/10.1172/JCI98047 DO - 10.1172/JCI98047 ID - Zamarin2018 ER - TY - JOUR AU - Demaria, S. AU - Golden, E. B. AU - Formenti, S. C. PY - 2015 DA - 2015// TI - Role of local radiation therapy in cancer immunotherapy JO - JAMA Oncol. VL - 1 UR - https://doi.org/10.1001/jamaoncol.2015.2756 DO - 10.1001/jamaoncol.2015.2756 ID - Demaria2015 ER - TY - JOUR AU - Alexander, G. S. AU - Palmer, J. D. AU - Tuluc, M. AU - Lin, J. AU - Dicker, A. P. AU - Bar-Ad, V. PY - 2016 DA - 2016// TI - Immune biomarkers of treatment failure for a patient on a phase I clinical trial of pembrolizumab plus radiotherapy JO - J Hematol Oncol. VL - 9 UR - https://doi.org/10.1186/s13045-016-0328-4 DO - 10.1186/s13045-016-0328-4 ID - Alexander2016 ER - TY - JOUR AU - Formenti, S. C. AU - Demaria, S. PY - 2012 DA - 2012// TI - Radiation therapy to convert the tumor into an in situ vaccine JO - Int J Radiat Oncol Biol Phys VL - 84 UR - https://doi.org/10.1016/j.ijrobp.2012.06.020 DO - 10.1016/j.ijrobp.2012.06.020 ID - Formenti2012 ER - TY - JOUR AU - Esposito, A. AU - Criscitiello, C. AU - Curigliano, G. PY - 2015 DA - 2015// TI - Immune checkpoint inhibitors with radiotherapy and locoregional treatment: synergism and potential clinical implications JO - Curr Opin Oncol VL - 27 UR - https://doi.org/10.1097/CCO.0000000000000225 DO - 10.1097/CCO.0000000000000225 ID - Esposito2015 ER - TY - JOUR AU - Ko, E. C. AU - Formenti, S. C. PY - 2018 DA - 2018// TI - Radiotherapy and checkpoint inhibitors: a winning new combination? JO - Ther Adv Med Oncol. VL - 10 UR - https://doi.org/10.1177/1758835918768240 DO - 10.1177/1758835918768240 ID - Ko2018 ER - TY - JOUR AU - Liu, Y. AU - Dong, Y. AU - Kong, L. AU - Shi, F. AU - Zhu, H. AU - Yu, J. PY - 2018 DA - 2018// TI - Abscopal effect of radiotherapy combined with immune checkpoint inhibitors JO - J Hematol Oncol. VL - 11 UR - https://doi.org/10.1186/s13045-018-0647-8 DO - 10.1186/s13045-018-0647-8 ID - Liu2018 ER - TY - JOUR AU - Aboudaram, A. AU - Modesto, A. AU - Chaltiel, L. AU - Gomez-Roca, C. AU - Boulinguez, S. AU - Sibaud, V. PY - 2017 DA - 2017// TI - Concurrent radiotherapy for patients with metastatic melanoma and receiving anti-programmed-death 1 therapy: a safe and effective combination JO - Melanoma Res VL - 27 UR - https://doi.org/10.1097/CMR.0000000000000386 DO - 10.1097/CMR.0000000000000386 ID - Aboudaram2017 ER - TY - JOUR AU - Fiorica, F. AU - Belluomini, L. AU - Stefanelli, A. AU - Santini, A. AU - Urbini, B. AU - Giorgi, C. PY - 2018 DA - 2018// TI - Immune checkpoint inhibitor nivolumab and radiotherapy in pretreated lung cancer patients: efficacy and safety of combination JO - Am J Clin Oncol UR - https://doi.org/10.1097/coc.0000000000000428 DO - 10.1097/coc.0000000000000428 ID - Fiorica2018 ER - TY - JOUR AU - Jiang, W. AU - Chan, C. K. AU - Weissman, I. L. AU - Kim, B. Y. S. AU - Hahn, S. M. PY - 2016 DA - 2016// TI - Immune priming of the tumor microenvironment by radiation JO - Trends Cancer. VL - 2 UR - https://doi.org/10.1016/j.trecan.2016.09.007 DO - 10.1016/j.trecan.2016.09.007 ID - Jiang2016 ER - TY - JOUR AU - Marin-Acevedo, J. A. AU - Soyano, A. E. AU - Dholaria, B. AU - Knutson, K. L. AU - Lou, Y. PY - 2018 DA - 2018// TI - Cancer immunotherapy beyond immune checkpoint inhibitors JO - J Hematol Oncol. VL - 11 UR - https://doi.org/10.1186/s13045-017-0552-6 DO - 10.1186/s13045-017-0552-6 ID - Marin-Acevedo2018 ER - TY - JOUR AU - Aurisicchio, L. AU - Pallocca, M. AU - Ciliberto, G. AU - Palombo, F. PY - 2018 DA - 2018// TI - The perfect personalized cancer therapy: cancer vaccines against neoantigens JO - J Exp Clin Cancer Res. VL - 37 UR - https://doi.org/10.1186/s13046-018-0751-1 DO - 10.1186/s13046-018-0751-1 ID - Aurisicchio2018 ER - TY - JOUR AU - Wang, Y. Q. AU - Wu, J. AU - Fan, Q. Z. AU - Zhou, M. AU - Yue, Z. G. AU - Ma, G. H. PY - 2014 DA - 2014// TI - Novel vaccine delivery system induces robust humoral and cellular immune responses based on multiple mechanisms JO - Adv Healthc Mater. VL - 3 UR - https://doi.org/10.1002/adhm.201300335 DO - 10.1002/adhm.201300335 ID - Wang2014 ER - TY - JOUR AU - Li, M. AU - Li, Y. AU - Peng, K. AU - Wang, Y. AU - Gong, T. AU - Zhang, Z. PY - 2017 DA - 2017// TI - Engineering intranasal mRNA vaccines to enhance lymph node trafficking and immune responses JO - Acta Biomater VL - 64 UR - https://doi.org/10.1016/j.actbio.2017.10.019 DO - 10.1016/j.actbio.2017.10.019 ID - Li2017 ER - TY - JOUR AU - Gubin, M. M. AU - Zhang, X. AU - Schuster, H. AU - Caron, E. AU - Ward, J. P. AU - Noguchi, T. PY - 2014 DA - 2014// TI - Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens JO - Nature VL - 515 UR - https://doi.org/10.1038/nature13988 DO - 10.1038/nature13988 ID - Gubin2014 ER - TY - JOUR AU - Ok, C. Y. AU - Young, K. H. PY - 2017 DA - 2017// TI - Checkpoint inhibitors in hematological malignancies JO - J Hematol Oncol. VL - 10 UR - https://doi.org/10.1186/s13045-017-0474-3 DO - 10.1186/s13045-017-0474-3 ID - Ok2017 ER - TY - JOUR AU - Munn, D. H. AU - Bronte, V. PY - 2016 DA - 2016// TI - Immune suppressive mechanisms in the tumor microenvironment JO - Curr Opin Immunol VL - 39 UR - https://doi.org/10.1016/j.coi.2015.10.009 DO - 10.1016/j.coi.2015.10.009 ID - Munn2016 ER - TY - JOUR AU - Sahin, U. AU - Derhovanessian, E. AU - Miller, M. AU - Kloke, B. P. AU - Simon, P. AU - Lower, M. PY - 2017 DA - 2017// TI - Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer JO - Nature VL - 547 UR - https://doi.org/10.1038/nature23003 DO - 10.1038/nature23003 ID - Sahin2017 ER - TY - JOUR AU - Ott, P. A. AU - Hu, Z. AU - Keskin, D. B. AU - Shukla, S. A. AU - Sun, J. AU - Bozym, D. J. PY - 2017 DA - 2017// TI - An immunogenic personal neoantigen vaccine for patients with melanoma JO - Nature VL - 547 UR - https://doi.org/10.1038/nature22991 DO - 10.1038/nature22991 ID - Ott2017 ER - TY - JOUR AU - Furness, A. J. AU - Quezada, S. A. AU - Peggs, K. S. PY - 2016 DA - 2016// TI - Neoantigen heterogeneity: a key driver of immune response and sensitivity to immune checkpoint blockade? JO - Immunotherapy. VL - 8 UR - https://doi.org/10.2217/imt-2016-0064 DO - 10.2217/imt-2016-0064 ID - Furness2016 ER - TY - JOUR AU - McGranahan, N. AU - Furness, A. J. AU - Rosenthal, R. AU - Ramskov, S. AU - Lyngaa, R. AU - Saini, S. K. PY - 2016 DA - 2016// TI - Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade JO - Science VL - 351 UR - https://doi.org/10.1126/science.aaf1490 DO - 10.1126/science.aaf1490 ID - McGranahan2016 ER - TY - JOUR AU - Mittal, D. AU - Gubin, M. M. AU - Schreiber, R. D. AU - Smyth, M. J. PY - 2014 DA - 2014// TI - New insights into cancer immunoediting and its three component phases-elimination, equilibrium and escape JO - Curr Opin Immunol VL - 27 UR - https://doi.org/10.1016/j.coi.2014.01.004 DO - 10.1016/j.coi.2014.01.004 ID - Mittal2014 ER - TY - JOUR AU - DuPage, M. AU - Mazumdar, C. AU - Schmidt, L. M. AU - Cheung, A. F. AU - Jacks, T. PY - 2012 DA - 2012// TI - Expression of tumour-specific antigens underlies cancer immunoediting JO - Nature VL - 482 UR - https://doi.org/10.1038/nature10803 DO - 10.1038/nature10803 ID - DuPage2012 ER - TY - JOUR AU - Carreno, B. M. AU - Magrini, V. AU - Becker-Hapak, M. AU - Kaabinejadian, S. AU - Hundal, J. AU - Petti, A. A. PY - 2015 DA - 2015// TI - Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells JO - Science VL - 348 UR - https://doi.org/10.1126/science.aaa3828 DO - 10.1126/science.aaa3828 ID - Carreno2015 ER - TY - JOUR AU - Marshall, H. T. AU - Djamgoz, M. B. A. PY - 2018 DA - 2018// TI - Immuno-oncology: emerging targets and combination therapies JO - Front Oncol. VL - 8 UR - https://doi.org/10.3389/fonc.2018.00315 DO - 10.3389/fonc.2018.00315 ID - Marshall2018 ER - TY - JOUR AU - Kato, T. AU - Matsuda, T. AU - Ikeda, Y. AU - Park, J. H. AU - Leisegang, M. AU - Yoshimura, S. PY - 2018 DA - 2018// TI - Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells JO - Oncotarget. VL - 9 UR - https://doi.org/10.18632/oncotarget.24232 DO - 10.18632/oncotarget.24232 ID - Kato2018 ER - TY - JOUR AU - Medavaram, S. AU - Zhang, Y. PY - 2018 DA - 2018// TI - Emerging therapies in advanced hepatocellular carcinoma JO - Exp Hematol Oncol. VL - 7 UR - https://doi.org/10.1186/s40164-018-0109-6 DO - 10.1186/s40164-018-0109-6 ID - Medavaram2018 ER - TY - JOUR AU - Tran, E. AU - Turcotte, S. AU - Gros, A. AU - Robbins, P. F. AU - Lu, Y. C. AU - Dudley, M. E. PY - 2014 DA - 2014// TI - Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer JO - Science VL - 344 UR - https://doi.org/10.1126/science.1251102 DO - 10.1126/science.1251102 ID - Tran2014 ER - TY - JOUR AU - Matsuda, T. AU - Leisegang, M. AU - Park, J. H. AU - Ren, L. AU - Kato, T. AU - Ikeda, Y. PY - 2018 DA - 2018// TI - Induction of neoantigen-specific cytotoxic T Cells and construction of T-cell receptor-engineered T cells for ovarian cancer JO - Clin Cancer Res VL - 24 UR - https://doi.org/10.1158/1078-0432.CCR-18-0142 DO - 10.1158/1078-0432.CCR-18-0142 ID - Matsuda2018 ER - TY - JOUR AU - Met, O. AU - Jensen, K. M. AU - Chamberlain, C. A. AU - Donia, M. AU - Svane, I. M. PY - 2018 DA - 2018// TI - Principles of adoptive T cell therapy in cancer JO - Semin Immunopathol UR - https://doi.org/10.1007/s00281-018-0703-z DO - 10.1007/s00281-018-0703-z ID - Met2018 ER - TY - JOUR AU - Rataj, F. AU - Kraus, F. B. T. AU - Chaloupka, M. AU - Grassmann, S. AU - Heise, C. AU - Cadilha, B. L. PY - 2018 DA - 2018// TI - PD1-CD28 fusion protein enables CD4+ T Cell help for adoptive T cell therapy in models of pancreatic cancer and non-hodgkin lymphoma JO - Front Immunol. VL - 9 UR - https://doi.org/10.3389/fimmu.2018.01955 DO - 10.3389/fimmu.2018.01955 ID - Rataj2018 ER - TY - JOUR AU - Chong, E. A. AU - Melenhorst, J. J. AU - Lacey, S. F. AU - Ambrose, D. E. AU - Gonzalez, V. AU - Levine, B. L. PY - 2017 DA - 2017// TI - PD-1 blockade modulates chimeric antigen receptor (CAR)-modified T cells: refueling the CAR JO - Blood VL - 129 UR - https://doi.org/10.1182/blood-2016-09-738245 DO - 10.1182/blood-2016-09-738245 ID - Chong2017 ER - TY - JOUR AU - Ligtenberg, M. A. AU - Pico de Coana, Y. AU - Shmushkovich, T. AU - Yoshimoto, Y. AU - Truxova, I. AU - Yang, Y. PY - 2018 DA - 2018// TI - Self-delivering RNAi targeting PD-1 improves tumor-specific T cell functionality for adoptive cell therapy of malignant melanoma JO - Mol Ther VL - 26 UR - https://doi.org/10.1016/j.ymthe.2018.04.015 DO - 10.1016/j.ymthe.2018.04.015 ID - Ligtenberg2018 ER - TY - JOUR AU - Lundegaard, C. AU - Lamberth, K. AU - Harndahl, M. AU - Buus, S. AU - Lund, O. AU - Nielsen, M. PY - 2008 DA - 2008// TI - NetMHC- 3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8–11 JO - Nucleic Acids Res VL - 36 UR - https://doi.org/10.1093/nar/gkn202 DO - 10.1093/nar/gkn202 ID - Lundegaard2008 ER - TY - JOUR AU - Nielsen, M. AU - Andreatta, M. PY - 2016 DA - 2016// TI - NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets JO - Genome Med. VL - 8 UR - https://doi.org/10.1186/s13073-016-0288-x DO - 10.1186/s13073-016-0288-x ID - Nielsen2016 ER - TY - JOUR AU - Jorgensen, K. W. AU - Rasmussen, M. AU - Buus, S. AU - Nielsen, M. PY - 2014 DA - 2014// TI - NetMHCstab—predicting stability of peptide-MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery JO - Immunology VL - 141 UR - https://doi.org/10.1111/imm.12160 DO - 10.1111/imm.12160 ID - Jorgensen2014 ER - TY - JOUR AU - Zhang, H. AU - Lund, O. AU - Nielsen, M. PY - 2009 DA - 2009// TI - The PickPocket method for predicting binding specificities for receptors based on receptor pocket similarities: application to MHC-peptide binding JO - Bioinformatics VL - 25 UR - https://doi.org/10.1093/bioinformatics/btp137 DO - 10.1093/bioinformatics/btp137 ID - Zhang2009 ER - TY - JOUR AU - Schubert, B. AU - Walzer, M. AU - Brachvogel, H. P. AU - Szolek, A. AU - Mohr, C. AU - Kohlbacher, O. PY - 2016 DA - 2016// TI - FRED 2: an immunoinformatics framework for Python JO - Bioinformatics VL - 32 UR - https://doi.org/10.1093/bioinformatics/btw113 DO - 10.1093/bioinformatics/btw113 ID - Schubert2016 ER - TY - JOUR AU - Larsen, M. V. AU - Lundegaard, C. AU - Lamberth, K. AU - Buus, S. AU - Lund, O. AU - Nielsen, M. PY - 2007 DA - 2007// TI - Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction JO - BMC Bioinform VL - 8 UR - https://doi.org/10.1186/1471-2105-8-424 DO - 10.1186/1471-2105-8-424 ID - Larsen2007 ER - TY - JOUR AU - Stranzl, T. AU - Larsen, M. V. AU - Lundegaard, C. AU - Nielsen, M. PY - 2010 DA - 2010// TI - NetCTLpan: pan-specific MHC class I pathway epitope predictions JO - Immunogenetics VL - 62 UR - https://doi.org/10.1007/s00251-010-0441-4 DO - 10.1007/s00251-010-0441-4 ID - Stranzl2010 ER - TY - JOUR AU - Hundal, J. AU - Carreno, B. M. AU - Petti, A. A. AU - Linette, G. P. AU - Griffith, O. L. AU - Mardis, E. R. PY - 2016 DA - 2016// TI - pVAC-Seq: a genome-guided in silico approach to identifying tumor neoantigens JO - Genome Med. VL - 8 UR - https://doi.org/10.1186/s13073-016-0264-5 DO - 10.1186/s13073-016-0264-5 ID - Hundal2016 ER - TY - JOUR AU - Schubert, B. AU - Brachvogel, H. P. AU - Jurges, C. AU - Kohlbacher, O. PY - 2015 DA - 2015// TI - EpiToolKit—a web-based workbench for vaccine design JO - Bioinformatics VL - 31 UR - https://doi.org/10.1093/bioinformatics/btv116 DO - 10.1093/bioinformatics/btv116 ID - Schubert2015 ER - TY - JOUR AU - Donnes, P. AU - Kohlbacher, O. PY - 2005 DA - 2005// TI - Integrated modeling of the major events in the MHC class I antigen processing pathway JO - Protein Sci VL - 14 UR - https://doi.org/10.1110/ps.051352405 DO - 10.1110/ps.051352405 ID - Donnes2005 ER -