Fig. 1From: Mechanisms for estrogen receptor expression in human cancerThe major ERα and ERβ isoforms. a There are three major isoforms of ERα, including ERα-66, ERα-46 and ERα36. ERα-36 differs with ERα-46 in the C-termini. b ERβ has five major isoforms, namely ERβ1, ERβ2, ERβ3, ERβ4 and ERβ5. AF1 activation function 1, AF2 activation function 2, DBD DNA-binding domain, LBD ligand-binding domainBack to article page