Table 1 Allele frequencies of HLA-C alleles in patients with MM and in controls
From: The association of HLA-C alleles with multiple myeloma in Chinese patients
HLA-C | MM (n = 316) | Control (n = 564,856) | P-value | OR | 95% CI | FDR P-value |
|---|---|---|---|---|---|---|
C*01:02 | 75 (11.8671%) | 179,483 (15.8875%) | 0.005706 | 0.713 | 0.560–0.907 | 0.0442 |
C*01:03 | 4 (0.6329%) | 7098 (0.6283%) | 1.000000 | 1.007 | 0.377–2.693 | 1.0333 |
C*01:06 | 1 (0.1582%) | 959 (0.08489%) | 0.415580 | 1.865 | 0.262–13.276 | 0.6135 |
C*02:02 | 5 (0.7911%) | 7796 (0.69009%) | 0.947008 | 1.148 | 0.476–2.768 | 1.0873 |
C*03:02 | 25 (3.9557%) | 67,104 (5.93195%) | 0.034862 | 0.652 | 0.437–0.973 | 0.1544 |
C*03:03 | 63 (9.9684%) | 78,335 (6.93407%) | 0.002686 | 1.486 | 1.145–1.928 | 0.0278 |
C*03:04 | 54 (8.5443%) | 112,096 (9.92253%) | 0.246598 | 0.848 | 0.642–1.121 | 0.4497 |
C*04:01 | 35 (5.5380%) | 65,172 (5.7689%) | 0.803415 | 0.958 | 0.681–1.347 | 1.0377 |
C*04:03 | 4 (0.6329%) | 11,488 (1.0169%) | 0.336047 | 0.620 | 0.232–1.657 | 0.5209 |
C*04:82 | 2 (0.3165%) | 2771 (0.24528%) | 1.000000 | 1.291 | 0.322–5.176 | 1.0000 |
C*05:01 | 2 (0.3165%) | 9626 (0.85208%) | 0.142966 | 0.369 | 0.092–1.480 | 0.3409 |
C*06:02 | 73 (11.5506%) | 100,031 (8.85456%) | 0.017080 | 1.344 | 1.053–1.716 | 0.1059 |
C*07:01 | 7 (1.1076%) | 6394 (0.56598%) | 0.121410 | 1.968 | 0.934–4.146 | 0.3136 |
C*07:02 | 78 (12.3418%) | 171,619 (15.19139%) | 0.046002 | 0.786 | 0.620–0.996 | 0.1585 |
C*07:04 | 6 (0.9494%) | 9810 (0.86836%) | 0.826323 | 1.094 | 0.490–2.445 | 1.0246 |
C*07:06 | 8 (1.2658%) | 9024 (0.79879%) | 0.187375 | 1.592 | 0.792–3.199 | 0.4149 |
C*07:154 | 1 (0.1582%) | 154 (0.01363%) | 0.083042 | 11.624 | 1.625–83.175 | 0.2340 |
C*07:63 | 2 (0.3165%) | 106 (0.00938%) | 0.001734 | 33.831 | 8.333–137.341 | 0.0269 |
C*08:01 | 54 (8.5443) | 96,496 (8.54165%) | 0.998093 | 1.000 | 0.757–1.322 | 1.0669 |
C*08:02 | 5 (0.7911%) | 3406 (0.30149%) | 0.059990 | 2.637 | 1.093–6.362 | 0.1860 |
C*08:03 | 8 (1.2658%) | 8754 (0.77489%) | 0.237989 | 1.642 | 0.817–3.298 | 0.4611 |
C*08:22 | 13 (2.0570%) | 9836 (0.87066%) | 0.001336 | 2.391 | 1.380–4.143 | 0.0414 |
C*12:02 | 29 (4.5886%) | 35,383 (3.13204%) | 0.035605 | 1.487 | 1.025–2.159 | 0.1380 |
C*12:03 | 16 (2.5316%) | 21,799 (1.92961%) | 0.271411 | 1.320 | 0.803–2.169 | 0.4674 |
C*14:02 | 23 (3.6392%) | 48,357 (4.28047%) | 0.425915 | 0.845 | 0.557–1.281 | 0.6002 |
C*14:03 | 9 (1.4241%) | 11,482 (1.01637%) | 0.307052 | 1.407 | 0.728–2.717 | 0.5010 |
C*15:02 | 21 (3.3228%) | 37,813 (3.34714%) | 0.972856 | 0.992 | 0.642–1.534 | 1.0771 |
C*15:04 | 1 (0.1582%) | 432 (0.03824%) | 0.215112 | 4.143 | 0.581–29.522 | 0.4446 |
C*15:05 | 3 (0.4747%) | 7914 (0.70053%) | 0.658438 | 0.676 | 0.217–2.102 | 0.8875 |
C*16:02 | 2 (0.3165%) | 2292 (0.20288%) | 0.847597 | 1.562 | 0.389–6.261 | 1.0106 |
C*17:01 | 3 (0.4747%) | 1154 (0.10215%) | 0.027885 | 4.664 | 1.498–14.522 | 0.1441 |