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Table 1 Allele frequencies of HLA-C alleles in patients with MM and in controls

From: The association of HLA-C alleles with multiple myeloma in Chinese patients

HLA-C MM (n = 316) Control (n = 564,856) P-value OR 95% CI FDR P-value
C*01:02 75 (11.8671%) 179,483 (15.8875%) 0.005706 0.713 0.560–0.907 0.0442
C*01:03 4 (0.6329%) 7098 (0.6283%) 1.000000 1.007 0.377–2.693 1.0333
C*01:06 1 (0.1582%) 959 (0.08489%) 0.415580 1.865 0.262–13.276 0.6135
C*02:02 5 (0.7911%) 7796 (0.69009%) 0.947008 1.148 0.476–2.768 1.0873
C*03:02 25 (3.9557%) 67,104 (5.93195%) 0.034862 0.652 0.437–0.973 0.1544
C*03:03 63 (9.9684%) 78,335 (6.93407%) 0.002686 1.486 1.145–1.928 0.0278
C*03:04 54 (8.5443%) 112,096 (9.92253%) 0.246598 0.848 0.642–1.121 0.4497
C*04:01 35 (5.5380%) 65,172 (5.7689%) 0.803415 0.958 0.681–1.347 1.0377
C*04:03 4 (0.6329%) 11,488 (1.0169%) 0.336047 0.620 0.232–1.657 0.5209
C*04:82 2 (0.3165%) 2771 (0.24528%) 1.000000 1.291 0.322–5.176 1.0000
C*05:01 2 (0.3165%) 9626 (0.85208%) 0.142966 0.369 0.092–1.480 0.3409
C*06:02 73 (11.5506%) 100,031 (8.85456%) 0.017080 1.344 1.053–1.716 0.1059
C*07:01 7 (1.1076%) 6394 (0.56598%) 0.121410 1.968 0.934–4.146 0.3136
C*07:02 78 (12.3418%) 171,619 (15.19139%) 0.046002 0.786 0.620–0.996 0.1585
C*07:04 6 (0.9494%) 9810 (0.86836%) 0.826323 1.094 0.490–2.445 1.0246
C*07:06 8 (1.2658%) 9024 (0.79879%) 0.187375 1.592 0.792–3.199 0.4149
C*07:154 1 (0.1582%) 154 (0.01363%) 0.083042 11.624 1.625–83.175 0.2340
C*07:63 2 (0.3165%) 106 (0.00938%) 0.001734 33.831 8.333–137.341 0.0269
C*08:01 54 (8.5443) 96,496 (8.54165%) 0.998093 1.000 0.757–1.322 1.0669
C*08:02 5 (0.7911%) 3406 (0.30149%) 0.059990 2.637 1.093–6.362 0.1860
C*08:03 8 (1.2658%) 8754 (0.77489%) 0.237989 1.642 0.817–3.298 0.4611
C*08:22 13 (2.0570%) 9836 (0.87066%) 0.001336 2.391 1.380–4.143 0.0414
C*12:02 29 (4.5886%) 35,383 (3.13204%) 0.035605 1.487 1.025–2.159 0.1380
C*12:03 16 (2.5316%) 21,799 (1.92961%) 0.271411 1.320 0.803–2.169 0.4674
C*14:02 23 (3.6392%) 48,357 (4.28047%) 0.425915 0.845 0.557–1.281 0.6002
C*14:03 9 (1.4241%) 11,482 (1.01637%) 0.307052 1.407 0.728–2.717 0.5010
C*15:02 21 (3.3228%) 37,813 (3.34714%) 0.972856 0.992 0.642–1.534 1.0771
C*15:04 1 (0.1582%) 432 (0.03824%) 0.215112 4.143 0.581–29.522 0.4446
C*15:05 3 (0.4747%) 7914 (0.70053%) 0.658438 0.676 0.217–2.102 0.8875
C*16:02 2 (0.3165%) 2292 (0.20288%) 0.847597 1.562 0.389–6.261 1.0106
C*17:01 3 (0.4747%) 1154 (0.10215%) 0.027885 4.664 1.498–14.522 0.1441
  1. Italic values indicate FDR < 0.05
  2. OR odds ratio, CI confidence interval, FDR false discovery rate