Fig. 6

Correlation of molecular and morphological responses over time in selected patients. Patients with BM-CR (MF-0/1, MF-1) and subsequent relapse. Blue arrows indicate time on active therapy. The number in the top left upper corner represents the patient # from Table 2. The red line indicates the JAK2 allele burden over time. The box in the bottom right corner shows the change in BM and response, NEG MPN = no signs of ET or PV, normal BM. The gray square represents the time of loss of HR (shown only in patients who lost their HR)