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Table 6 Comparative results of statistically significant (p < 0.05) prognostic factors in major studies reported worldwide and compared to this study

From: Post-transplant lymphoproliferative disorder (PTLD): single institutional experience of 141 patients

Study

Leblond et al. [23]

Jain et al. [24]

Ghobrial et al. [25]

Maecker et al. [26]

Oton et al. [27]

Knight et al. [28]

Evens et al. [29]

Kinch et al. [30]

Dierickx et al. [31]

Montanari et al. [32]

Luskin et al. [33]

This study

Year

2001

2002

2005

2007

2008

2009

2010

2013

2013

2015

2015

2017

Subjects (n)

61

170

107

55

84

78

80

135

140

120

176

141

Advanced age at diagnosis

NSS

NSS

SS

    

SS

SS

SS

SS

SS

Performance status

SS

 

SS

 

SS

NSS

SS

SS

SS

SS

 

SS

Late PTLD onset

Poor (NSS)

NSS

NSS

NSS

Good (SS)

 

NSS

 

NSS

NSS

 

NSS

Gender

NSS

F > M (NSS)

NSS

    

NSS

 

NSS

 

F > M (SS)

Extra-nodal site

SS

 

SS

SS

SS

NSS

SS

SS

SS

NSS

SS

SS

CD20 +

  

NSS

     

NSS

SS

 

NSS

Low albumin

      

SS

 

SS

NSS

 

NSS

High LDH

NSS

 

SS

   

NSS

SS

SS

NSS

SS

NSS

B-symptoms

     

NSS

 

SS

  

NSS

NSS

Allograft type

NSS

 

NSS

NSS

   

SS

 

NSS

SS

SS

Non EBV PTLD

SS

NSS

 

NS

   

SS

 

NSS

NSS

NSS

Advanced stage

NS

 

SS

SS

SS

SS

NSS

SS

SS

NSS

SS

NSS

PTLD type/grade

NSS

SS

 

NSS

    

SS

NSS

NSS

SS

Higher IPI

NSS

 

SS

  

SS

NSS

 

SS

  

SS

Initial response

  

SS

SS

       

SS

Rituximab use

  

NSS

 

SS

 

SS

  

NSS

 

NSS

  1. SS statistically significant, NSS not statistically significant