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Table 1 Correlation between c-maf expression and disease characteristics of multiple myeloma patients

From: Clinical implications of c-maf expression in plasma cells from patients with multiple myeloma

Characteristics

All patients (n = 128)

C-maf-positive (n = 39)

C-maf-negative (n = 89)

p value

Sex, F/M

44/84

11/28

33/56

0.331

Age, years, n (%)

 ≤60

66 (51.6)

20 (51.3)

46 (51.7)

 

 >60

62 (48.4)

19 (48.7)

43 (48.3)

0.966

Isotype, IgH, n (%)

 IgA

31 (24.2)

9 (23.1)

22 (24.7)

 

 IgD

6 (4.7)

1 (2.6)

5 (5.6)

 

 IgG

55 (43.0)

21 (53.8)

34 (38.2)

 

 Light chains

36 (28.1)

8 (20.5)

28 (31.5)

0.342

Isotype, IgL, n (%)

 κ

60 (46.9)

17 (43.6)

43 (48.3)

 

 λ

68 (53.1)

22 (56.4)

46 (51.7)

0.622

D–S stage, n (%)

 1A + 2A

14 (10.9)

2 (5.1)

12 (13.5)

 

 3A

85 (66.4)

30 (76.9)

55 (61.8)

 

 3B

29 (22.7)

7 (17.9)

22 (24.7)

0.176

ISS stage, n (%)

 I + II

72 (56.3)

20 (51.3)

52 (58.4)

 

 III

56 (43.8)

19 (48.7)

37 (41.6)

0.453

Alb level, n (%)

 ≥35 g/L

65 (50.8)

14 (35.9)

51 (57.3)

 

 <35 g/L

63 (49.2)

25 (64.1)

38 (42.7)

0.026

β2-MG level, n (%)

 ≤2500 μg/L

25 (19.5)

2 (5.1)

23 (25.8)

 

 >2500 μg/L

103 (80.5)

37 (94.9)

66 (74.2)

0.007

Hb, n (%)

 <80 g/L

63 (49.2)

21 (53.8)

42 (47.2)

 

 ≥80 g/L

65 (50.8)

18 (46.2)

47 (52.8)

0.488

Plt, n (%)

 ≤140 × 109/L

62 (48.4)

20 (51.3)

42 (47.2)

 

 >140 × 109/L

66 (51.6)

19 (48.7)

47 (52.8)

0.670

Calcium level, n (%)

 ≤2.54 mmol/L

110 (85.9)

35 (89.7)

75 (84.3)

 

 >2.54 mmol/L

18 (14.1)

4 (10.2)

14 (15.7)

0.412

CRP level, n (%)

 ≤8.0 mg/L

92 (71.9)

29 (74.4)

63 (70.8)

 

 >8.0 mg/L

36 (28.1)

10 (25.6)

26 (29.2)

0.679

LDH level, n (%)

 ≤250 U/L

105 (82.0)

31 (79.5)

74 (79.8)

 

 >250 U/L

23 (18.0)

8 (20.5)

15 (20.2)

0.620

  1. ISS international stage system, Alb albumin, β2-MG β2-microglobulin, CRP c-reactive protein, LDH lactate dehydrogenase