Skip to main content

Table 1 Correlation between c-maf expression and disease characteristics of multiple myeloma patients

From: Clinical implications of c-maf expression in plasma cells from patients with multiple myeloma

Characteristics All patients (n = 128) C-maf-positive (n = 39) C-maf-negative (n = 89) p value
Sex, F/M 44/84 11/28 33/56 0.331
Age, years, n (%)
 ≤60 66 (51.6) 20 (51.3) 46 (51.7)  
 >60 62 (48.4) 19 (48.7) 43 (48.3) 0.966
Isotype, IgH, n (%)
 IgA 31 (24.2) 9 (23.1) 22 (24.7)  
 IgD 6 (4.7) 1 (2.6) 5 (5.6)  
 IgG 55 (43.0) 21 (53.8) 34 (38.2)  
 Light chains 36 (28.1) 8 (20.5) 28 (31.5) 0.342
Isotype, IgL, n (%)
 κ 60 (46.9) 17 (43.6) 43 (48.3)  
 λ 68 (53.1) 22 (56.4) 46 (51.7) 0.622
D–S stage, n (%)
 1A + 2A 14 (10.9) 2 (5.1) 12 (13.5)  
 3A 85 (66.4) 30 (76.9) 55 (61.8)  
 3B 29 (22.7) 7 (17.9) 22 (24.7) 0.176
ISS stage, n (%)
 I + II 72 (56.3) 20 (51.3) 52 (58.4)  
 III 56 (43.8) 19 (48.7) 37 (41.6) 0.453
Alb level, n (%)
 ≥35 g/L 65 (50.8) 14 (35.9) 51 (57.3)  
 <35 g/L 63 (49.2) 25 (64.1) 38 (42.7) 0.026
β2-MG level, n (%)
 ≤2500 μg/L 25 (19.5) 2 (5.1) 23 (25.8)  
 >2500 μg/L 103 (80.5) 37 (94.9) 66 (74.2) 0.007
Hb, n (%)
 <80 g/L 63 (49.2) 21 (53.8) 42 (47.2)  
 ≥80 g/L 65 (50.8) 18 (46.2) 47 (52.8) 0.488
Plt, n (%)
 ≤140 × 109/L 62 (48.4) 20 (51.3) 42 (47.2)  
 >140 × 109/L 66 (51.6) 19 (48.7) 47 (52.8) 0.670
Calcium level, n (%)
 ≤2.54 mmol/L 110 (85.9) 35 (89.7) 75 (84.3)  
 >2.54 mmol/L 18 (14.1) 4 (10.2) 14 (15.7) 0.412
CRP level, n (%)
 ≤8.0 mg/L 92 (71.9) 29 (74.4) 63 (70.8)  
 >8.0 mg/L 36 (28.1) 10 (25.6) 26 (29.2) 0.679
LDH level, n (%)
 ≤250 U/L 105 (82.0) 31 (79.5) 74 (79.8)  
 >250 U/L 23 (18.0) 8 (20.5) 15 (20.2) 0.620
  1. ISS international stage system, Alb albumin, β2-MG β2-microglobulin, CRP c-reactive protein, LDH lactate dehydrogenase