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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2 V617F allelic burden

Fig. 5

Changes in T cell subsets vary based on molecular response. Patients treated with PegINFα were separated into R and NR subsets based on a 20 % decrease in JAK2 V617 allelic burden. PBMC were analyzed as described above and fold changes compare to baseline were examined. a represents 23 patient samples (10R and 13 NR), b, c include 16 patients (6R and 10NR), and d includes 13 patients (4R and 9 NR). ac show frequency of Treg, dividing Treg, CD39+ HLA-DR+ Treg and Helios+ Treg. d shows CD38+ HLA-DR+ T cells in R vs NR

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