Fig. 3From: Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2 V617F allelic burdenExpression of checkpoint molecules is increased by PegINFα. CD3+ CD4+T cells in peripheral blood were separated into Treg and non-Treg based on the expression of Foxp3. Foxp3+ Treg, (a and c) or Foxp3− non-Treg (b and d) were examined for expression of CTLA-4 (a–b) and PD-1 (c–d)Back to article page