TY - JOUR AU - Liu, Y. L. AU - Castleberry, R. P. AU - Emanuel, P. D. PY - 2009 DA - 2009// TI - PTEN deficiency is a common defect in juvenile myelomonocytic leukemia JO - Leuk Res VL - 33 UR - https://doi.org/10.1016/j.leukres.2008.09.036 DO - 10.1016/j.leukres.2008.09.036 ID - Liu2009 ER - TY - JOUR AU - Gutierrez, A. AU - Sanda, T. AU - Grebliunaite, R. AU - Carracedo, A. AU - Salmena, L. AU - Ahn, Y. PY - 2009 DA - 2009// TI - High frequency of PTEN, PI3K and AKT abnormalities in T-cell acute lymphoblastic leukemia JO - Blood VL - 114 UR - https://doi.org/10.1182/blood-2009-02-206722 DO - 10.1182/blood-2009-02-206722 ID - Gutierrez2009 ER - TY - JOUR AU - Rossi, D. J. AU - Weissman, I. L. PY - 2006 DA - 2006// TI - Pten, tumorigenesis, and stem cell self-renewal JO - Cell VL - 125 UR - https://doi.org/10.1016/j.cell.2006.04.006 DO - 10.1016/j.cell.2006.04.006 ID - Rossi2006 ER - TY - JOUR AU - Chu, I. M. AU - Hengst, L. AU - Slingerland, J. M. PY - 2008 DA - 2008// TI - The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy JO - Nat Rev Cancer VL - 8 UR - https://doi.org/10.1038/nrc2347 DO - 10.1038/nrc2347 ID - Chu2008 ER - TY - JOUR AU - Komuro, H. AU - Valentine, M. B. AU - Rubnitz, J. E. AU - Saito, M. AU - Raimondi, S. C. AU - Carroll, A. J. PY - 1999 DA - 1999// TI - p27KIP1 deletions in childhood acute lymphoblastic leukemia JO - Neoplasia VL - 1 UR - https://doi.org/10.1038/sj.neo.7900033 DO - 10.1038/sj.neo.7900033 ID - Komuro1999 ER - TY - JOUR AU - Haferlach, C. AU - Bacher, U. AU - Kohlmann, A. AU - Schindela, S. AU - Alpermann, T. AU - Kern, W. PY - 2011 DA - 2011// TI - CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia JO - Haematologica VL - 96 UR - https://doi.org/10.3324/haematol.2010.035584 DO - 10.3324/haematol.2010.035584 ID - Haferlach2011 ER - TY - JOUR AU - Dietrich, S. AU - Hullein, J. AU - Lee, S. C. AU - Hutter, B. AU - Gonzalez, D. AU - Jayne, S. PY - 2015 DA - 2015// TI - Recurrent CDKN1B (p27) mutations in hairy cell leukemia JO - Blood VL - 126 UR - https://doi.org/10.1182/blood-2015-04-643361 DO - 10.1182/blood-2015-04-643361 ID - Dietrich2015 ER - TY - JOUR AU - Cristofano, A. AU - Acetis, M. AU - Koff, A. AU - Cordon-Cardo, C. AU - Pandolfi, P. P. PY - 2001 DA - 2001// TI - Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse JO - Nat Genet VL - 27 UR - https://doi.org/10.1038/84879 DO - 10.1038/84879 ID - Cristofano2001 ER - TY - JOUR AU - Uner, A. H. AU - Saglam, A. AU - Han, U. AU - Hayran, M. AU - Sungur, A. AU - Ruacan, S. PY - 2005 DA - 2005// TI - PTEN and p27 expression in mature T-cell and NK-cell neoplasms JO - Leuk Lymphoma VL - 46 UR - https://doi.org/10.1080/10428190500144813 DO - 10.1080/10428190500144813 ID - Uner2005 ER - TY - JOUR AU - Halvorsen, O. J. AU - Haukaas, S. A. AU - Akslen, L. A. PY - 2003 DA - 2003// TI - Combined loss of PTEN and p27 expression is associated with tumor cell proliferation by Ki-67 and increased risk of recurrent disease in localized prostate cancer JO - Clin Cancer Res VL - 9 ID - Halvorsen2003 ER - TY - JOUR AU - Fero, M. L. AU - Rivkin, M. AU - Tasch, M. AU - Porter, P. AU - Carow, C. E. AU - Firpo, E. PY - 1996 DA - 1996// TI - A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice JO - Cell VL - 85 UR - https://doi.org/10.1016/S0092-8674(00)81239-8 DO - 10.1016/S0092-8674(00)81239-8 ID - Fero1996 ER - TY - JOUR AU - Guo, W. AU - Lasky, J. L. AU - Chang, C. J. AU - Mosessian, S. AU - Lewis, X. AU - Xiao, Y. PY - 2008 DA - 2008// TI - Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation JO - Nature VL - 453 UR - https://doi.org/10.1038/nature06933 DO - 10.1038/nature06933 ID - Guo2008 ER - TY - JOUR AU - Wey, S. AU - Luo, B. AU - Tseng, C. C. AU - Ni, M. AU - Zhou, H. AU - Fu, Y. PY - 2012 DA - 2012// TI - Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling JO - Blood VL - 119 UR - https://doi.org/10.1182/blood-2011-06-357384 DO - 10.1182/blood-2011-06-357384 ID - Wey2012 ER - TY - JOUR AU - Kogan, S. C. AU - Ward, J. M. AU - Anver, M. R. AU - Berman, J. J. AU - Brayton, C. AU - Cardiff, R. D. PY - 2002 DA - 2002// TI - Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice JO - Blood VL - 100 UR - https://doi.org/10.1182/blood.V100.1.238 DO - 10.1182/blood.V100.1.238 ID - Kogan2002 ER - TY - JOUR AU - Sun, H. AU - Lesche, R. AU - Li, D. M. AU - Liliental, J. AU - Zhang, H. AU - Gao, J. PY - 1999 DA - 1999// TI - PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway JO - Proc Natl Acad Sci USA VL - 96 UR - https://doi.org/10.1073/pnas.96.11.6199 DO - 10.1073/pnas.96.11.6199 ID - Sun1999 ER - TY - JOUR AU - Kurose, K. AU - Zhou, X. P. AU - Araki, T. AU - Cannistra, S. A. AU - Maher, E. R. AU - Eng, C. PY - 2001 DA - 2001// TI - Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas JO - Am J Pathol VL - 158 UR - https://doi.org/10.1016/S0002-9440(10)64681-0 DO - 10.1016/S0002-9440(10)64681-0 ID - Kurose2001 ER - TY - JOUR AU - Bartalucci, N. AU - Tozzi, L. AU - Bogani, C. AU - Martinelli, S. AU - Rotunno, G. AU - Villeval, J. L. PY - 2013 DA - 2013// TI - Co-targeting the PI3K/mTOR and JAK2 signalling pathways produces synergistic activity against myeloproliferative neoplasms JO - J Cell Mol Med VL - 17 UR - https://doi.org/10.1111/jcmm.12162 DO - 10.1111/jcmm.12162 ID - Bartalucci2013 ER - TY - JOUR AU - Nagai, Y. AU - Kawahara, M. AU - Sugino, N. AU - Shimazu, Y. AU - Hishizawa, M. AU - Yamashita, K. PY - 2014 DA - 2014// TI - A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation JO - Exp Hematol Oncol VL - 3 UR - https://doi.org/10.1186/2162-3619-3-6 DO - 10.1186/2162-3619-3-6 ID - Nagai2014 ER - TY - JOUR AU - Reddy, P. AU - Liu, L. AU - Adhikari, D. AU - Jagarlamudi, K. AU - Rajareddy, S. AU - Shen, Y. PY - 2008 DA - 2008// TI - Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool JO - Science VL - 319 UR - https://doi.org/10.1126/science.1152257 DO - 10.1126/science.1152257 ID - Reddy2008 ER - TY - JOUR AU - Rajareddy, S. AU - Reddy, P. AU - Du, C. AU - Liu, L. AU - Jagarlamudi, K. AU - Tang, W. PY - 2007 DA - 2007// TI - p27kip1 (cyclin-dependent kinase inhibitor 1B) controls ovarian development by suppressing follicle endowment and activation and promoting follicle atresia in mice JO - Mol Endocrinol VL - 21 UR - https://doi.org/10.1210/me.2007-0172 DO - 10.1210/me.2007-0172 ID - Rajareddy2007 ER -