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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: Nucleotide excision repair deficiency in melanoma in response to UVA

Fig. 5

Relative expression (RE) of GGR transcripts a XPC, b DDB1, and c DDB2 following UVA irradiation in p53- and p53 + melanoma cell lines. p53 mutant/null (p53−; Sk-Mel-28, Me4405) and p53 wildtype (p53+; MM200, Mel-RM melanoma cell lines were irradiated with 100 kJ/m2 UVA, then RE at baseline and 1, 4, 24, and 48 h post-irradiation was determined. Points mean of triplicate determinations of three independent experiments; bars ± SEM. Significant differences between groups were determined by Mann–Whitney U test. *p < 0.05, **p < 0.005, ***p < 0.000

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