Fig. 4
From: Nucleotide excision repair deficiency in melanoma in response to UVA
Expression of p53 following UVA irradiation in melanocytes and melanoma. Cell lines were irradiated with 100 kJ/m2 UVA, then mRNA transcript relative expression (RE) at baseline and 1, 4, 24, and 48 h post-irradiation was determined. a RE of p53 mRNA transcript. Significance compared to melanocytes (HEMaLP) determined by Mann–Whitney U test. *p < 0.05. Points mean of triplicate determinations of three independent experiments; bars ± SEM. b Western blot of p53 for all cell lines before and after UVA. Blots are representative of duplicate blots run for all proteins and cell lines