Fig. 1
From: Identification of AIM2 as a downstream target of JAK2V617F
Creation of the Tet-inducible JAK2V617F-expressing cell line D9. a A schematic representation of the Tet-inducible construct containing the JAK2V617F gene tagged with a V5 epitope. b Confirmation of JAK2V617F induction. Equal amounts of protein prepared from clones treated with Tet or vehicle alone for 24Â h were subjected to immunoblotting analysis using an anti V5 antibody to detect JAK2V617F