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Fig. 4 | Experimental Hematology & Oncology

Fig. 4

From: Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL)

Fig. 4

Protein phosphorylation profiles in Philadelphia chromosome negative pediatric BCP-ALL patients. Western blot analysis of 14 pediatric BCP-ALL samples; seven Philadelphia negative IKZF1 wild type, six Philadelphia negative IKZF1 deleted patients, and one Philadelphia positive IKZF1 deleted patient showing phosphorylation expression levels of a selection of proteins. The results show a great diversity in phosphorylation levels between the different ALL samples independently of IKZF1 status and other copy number alterations.

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