Fig. 3
From: Melanoma tumor growth is accelerated in a mouse model of sickle cell disease
Hemin induces HO-1 expression in cultured endothelial cells and promotes angiogenesis from aortic rings. a HO-1 expression level in bEend.3 cells treated with DMSO (control), 1 μM hemin or 5 μM hemin. b Quantification of sprouts from aortic rings treated with DMSO (control), 1 μM hemin or 1 μM hemin with 2.5 μM ZnPP. c Representative images of sprouts from aortic rings treated with DMSO, 1 μM hemin or 1 μM hemin with 2.5 μM ZnPP. Scale bar = 500 μm