Fig. 2
From: Melanoma tumor growth is accelerated in a mouse model of sickle cell disease
Accelerated tumor growth in SCD mice is prevented with suppression of HO-1. a Growth curves of WT mice (n = 10), SCD mice (n = 11), WT mice treated with ZnPP (n = 8) and SCD mice treated with ZnPP (n = 6). b Tumor weights of WT mice (n = 10), SCD mice (n = 11), WT mice treated with ZnPP (n = 8) and SCD mice treated with ZnPP (n = 6). c Representative image of blood vessel (CD31) staining in tumor hot spots from the 4 groups of mice, d Quantification of blood vessel density of tumors from the 4 groups of mice. Scale bar =100 μm. e Correlation of tumor weight and blood vessel density in SCD mice. f Correlation of blood vessel density and HO-1 activity in SCD mice. g Correlation of tumor weight and HO-1 activity in SCD mice