TY - JOUR AU - Kim, J. W. AU - Dang, C. V. PY - 2006 DA - 2006// TI - Cancer’s molecular sweet tooth and the Warburg effect JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-06-1501 DO - 10.1158/0008-5472.CAN-06-1501 ID - Kim2006 ER - TY - JOUR AU - Brizel, D. M. AU - Schroeder, T. AU - Scher, R. L. AU - Walenta, S. AU - Clough, R. W. AU - Dewhirst, M. W. PY - 2001 DA - 2001// TI - Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer JO - Int J Radiat Oncol Biol Phys VL - 51 UR - https://doi.org/10.1016/S0360-3016(01)01630-3 DO - 10.1016/S0360-3016(01)01630-3 ID - Brizel2001 ER - TY - JOUR AU - Walenta, S. AU - Wetterling, M. AU - Lehrke, M. AU - Schwickert, G. AU - Sundfor, K. AU - Rofstad, E. K. PY - 2000 DA - 2000// TI - High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers JO - Cancer Res VL - 60 ID - Walenta2000 ER - TY - JOUR AU - Quennet, V. AU - Yaromina, A. AU - Zips, D. AU - Rosner, A. AU - Walenta, S. AU - Baumann, M. PY - 2006 DA - 2006// TI - Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice JO - Radiother Oncol VL - 81 UR - https://doi.org/10.1016/j.radonc.2006.08.012 DO - 10.1016/j.radonc.2006.08.012 ID - Quennet2006 ER - TY - JOUR AU - Kennedy, K. M. AU - Dewhirst, M. W. PY - 2010 DA - 2010// TI - Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation JO - Future Oncol VL - 6 UR - https://doi.org/10.2217/fon.09.145 DO - 10.2217/fon.09.145 ID - Kennedy2010 ER - TY - JOUR AU - Draoui, N. AU - Feron, O. PY - 2011 DA - 2011// TI - Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments JO - Dis Model Mech VL - 4 UR - https://doi.org/10.1242/dmm.007724 DO - 10.1242/dmm.007724 ID - Draoui2011 ER - TY - JOUR AU - Halestrap, A. P. PY - 2012 DA - 2012// TI - The monocarboxylate transporter family–Structure and functional characterization JO - IUBMB Life VL - 64 UR - https://doi.org/10.1002/iub.573 DO - 10.1002/iub.573 ID - Halestrap2012 ER - TY - JOUR AU - Halestrap, A. P. AU - Meredith, D. PY - 2004 DA - 2004// TI - The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond JO - Pflugers Arch VL - 447 UR - https://doi.org/10.1007/s00424-003-1067-2 DO - 10.1007/s00424-003-1067-2 ID - Halestrap2004 ER - TY - JOUR AU - Kirk, P. AU - Wilson, M. C. AU - Heddle, C. AU - Brown, M. H. AU - Barclay, A. N. AU - Halestrap, A. P. PY - 2000 DA - 2000// TI - CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression JO - EMBO J VL - 19 UR - https://doi.org/10.1093/emboj/19.15.3896 DO - 10.1093/emboj/19.15.3896 ID - Kirk2000 ER - TY - JOUR AU - Wilson, M. C. AU - Meredith, D. AU - Halestrap, A. P. PY - 2002 DA - 2002// TI - Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M109658200 DO - 10.1074/jbc.M109658200 ID - Wilson2002 ER - TY - JOUR AU - Nabeshima, K. AU - Iwasaki, H. AU - Koga, K. AU - Hojo, H. AU - Suzumiya, J. AU - Kikuchi, M. PY - 2006 DA - 2006// TI - Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression JO - Pathol Int VL - 56 UR - https://doi.org/10.1111/j.1440-1827.2006.01972.x DO - 10.1111/j.1440-1827.2006.01972.x ID - Nabeshima2006 ER - TY - JOUR AU - Pinheiro, C. AU - Longatto-Filho, A. AU - Azevedo-Silva, J. AU - Casal, M. AU - Schmitt, F. C. AU - Baltazar, F. PY - 2012 DA - 2012// TI - Role of monocarboxylate transporters in human cancers: state of the art JO - J Bioenerg Biomembr VL - 44 UR - https://doi.org/10.1007/s10863-012-9428-1 DO - 10.1007/s10863-012-9428-1 ID - Pinheiro2012 ER - TY - JOUR AU - Walters, D. K. AU - Arendt, B. K. AU - Jelinek, D. F. PY - 2013 DA - 2013// TI - CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells JO - Cell Cycle VL - 12 UR - https://doi.org/10.4161/cc.26193 DO - 10.4161/cc.26193 ID - Walters2013 ER - TY - JOUR AU - Fujiwara, S. AU - Kawano, Y. AU - Yuki, H. AU - Okuno, Y. AU - Nosaka, K. AU - Mitsuya, H. PY - 2013 DA - 2013// TI - PDK1 inhibition is a novel therapeutic target in multiple myeloma JO - Br J Cancer VL - 108 UR - https://doi.org/10.1038/bjc.2013.51 DO - 10.1038/bjc.2013.51 ID - Fujiwara2013 ER - TY - JOUR AU - Sonveaux, P. AU - Vegran, F. AU - Schroeder, T. AU - Wergin, M. C. AU - Verrax, J. AU - Rabbani, Z. N. PY - 2008 DA - 2008// TI - Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice JO - J Clin Invest VL - 118 ID - Sonveaux2008 ER - TY - JOUR AU - Doherty, J. R. AU - Cleveland, J. L. PY - 2013 DA - 2013// TI - Targeting lactate metabolism for cancer therapeutics JO - J Clin Invest VL - 123 UR - https://doi.org/10.1172/JCI69741 DO - 10.1172/JCI69741 ID - Doherty2013 ER - TY - JOUR AU - Martinez-Outschoorn, U. E. AU - Whitaker-Menezes, D. AU - Valsecchi, M. AU - Martinez-Cantarin, M. P. AU - Dulau-Florea, A. AU - Gong, J. PY - 2013 DA - 2013// TI - Reverse Warburg effect in a patient with aggressive B-cell lymphoma: is lactic acidosis a paraneoplastic syndrome? JO - Semin Oncol VL - 40 UR - https://doi.org/10.1053/j.seminoncol.2013.04.016 DO - 10.1053/j.seminoncol.2013.04.016 ID - Martinez-Outschoorn2013 ER - TY - JOUR AU - Busk, M. AU - Walenta, S. AU - Mueller-Klieser, W. AU - Steiniche, T. AU - Jakobsen, S. AU - Horsman, M. R. PY - 2011 DA - 2011// TI - Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment JO - Radiother Oncol VL - 99 UR - https://doi.org/10.1016/j.radonc.2011.05.053 DO - 10.1016/j.radonc.2011.05.053 ID - Busk2011 ER - TY - JOUR AU - Hirschhaeuser, F. AU - Sattler, U. G. AU - Mueller-Klieser, W. PY - 2011 DA - 2011// TI - Lactate: a metabolic key player in cancer JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-11-1457 DO - 10.1158/0008-5472.CAN-11-1457 ID - Hirschhaeuser2011 ER - TY - JOUR AU - Walenta, S. AU - Chau, T. V. AU - Schroeder, T. AU - Lehr, H. A. AU - Kunz-Schughart, L. A. AU - Fuerst, A. PY - 2003 DA - 2003// TI - Metabolic classification of human rectal adenocarcinomas: a novel guideline for clinical oncologists? JO - J Cancer Res Clin Oncol VL - 129 UR - https://doi.org/10.1007/s00432-003-0450-x DO - 10.1007/s00432-003-0450-x ID - Walenta2003 ER - TY - JOUR AU - Yokota, H. AU - Guo, J. AU - Matoba, M. AU - Higashi, K. AU - Tonami, H. AU - Nagao, Y. PY - 2007 DA - 2007// TI - Lactate, choline, and creatine levels measured by vitro 1H-MRS as prognostic parameters in patients with non-small-cell lung cancer JO - J Magn Reson Imaging VL - 25 UR - https://doi.org/10.1002/jmri.20902 DO - 10.1002/jmri.20902 ID - Yokota2007 ER - TY - JOUR AU - Kang, K. W. AU - Im, Y. B. AU - Go, W. J. AU - Han, H. K. PY - 2009 DA - 2009// TI - C-myc amplification altered the gene expression of ABC- and SLC-transporters in human breast epithelial cells JO - Mol Pharm VL - 6 UR - https://doi.org/10.1021/mp800116f DO - 10.1021/mp800116f ID - Kang2009 ER - TY - JOUR AU - Coller, H. A. AU - Grandori, C. AU - Tamayo, P. AU - Colbert, T. AU - Lander, E. S. AU - Eisenman, R. N. PY - 2000 DA - 2000// TI - Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion JO - Proc Natl Acad Sci U S A VL - 97 UR - https://doi.org/10.1073/pnas.97.7.3260 DO - 10.1073/pnas.97.7.3260 ID - Coller2000 ER - TY - JOUR AU - Schuhmacher, M. AU - Kohlhuber, F. AU - Holzel, M. AU - Kaiser, C. AU - Burtscher, H. AU - Jarsch, M. PY - 2001 DA - 2001// TI - The transcriptional program of a human B cell line in response to Myc JO - Nucleic Acids Res VL - 29 UR - https://doi.org/10.1093/nar/29.2.397 DO - 10.1093/nar/29.2.397 ID - Schuhmacher2001 ER - TY - JOUR AU - Doherty, J. R. AU - Yang, C. AU - Scott, K. E. AU - Cameron, M. D. AU - Fallahi, M. AU - Li, W. PY - 2014 DA - 2014// TI - Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis JO - Cancer Res VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-2034 DO - 10.1158/0008-5472.CAN-13-2034 ID - Doherty2014 ER - TY - JOUR AU - Zhao, Z. AU - Wu, M. S. AU - Zou, C. AU - Tang, Q. AU - Lu, J. AU - Liu, D. PY - 2014 DA - 2014// TI - Downregulation of MCT1 inhibits tumor growth, metastasis and enhances chemotherapeutic efficacy in osteosarcoma through regulation of the NF-kappaB pathway JO - Cancer Lett VL - 342 UR - https://doi.org/10.1016/j.canlet.2013.08.042 DO - 10.1016/j.canlet.2013.08.042 ID - Zhao2014 ER - TY - JOUR AU - Miranda-Goncalves, V. AU - Honavar, M. AU - Pinheiro, C. AU - Martinho, O. AU - Pires, M. M. AU - Pinheiro, C. PY - 2013 DA - 2013// TI - Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets JO - Neuro Oncol VL - 15 UR - https://doi.org/10.1093/neuonc/nos298 DO - 10.1093/neuonc/nos298 ID - Miranda-Goncalves2013 ER - TY - JOUR AU - Kumar, A. AU - Kant, S. AU - Singh, S. M. PY - 2013 DA - 2013// TI - Targeting monocarboxylate transporter by alpha-cyano-4-hydroxycinnamate modulates apoptosis and cisplatin resistance of Colo205 cells: implication of altered cell survival regulation JO - Apoptosis VL - 18 UR - https://doi.org/10.1007/s10495-013-0894-7 DO - 10.1007/s10495-013-0894-7 ID - Kumar2013 ER - TY - JOUR AU - Diers, A. R. AU - Broniowska, K. A. AU - Chang, C. F. AU - Hogg, N. PY - 2012 DA - 2012// TI - Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition JO - Biochem J VL - 444 UR - https://doi.org/10.1042/BJ20120294 DO - 10.1042/BJ20120294 ID - Diers2012 ER - TY - JOUR AU - Ohtsuki, T. AU - Yawata, Y. AU - Wada, H. AU - Sugihara, T. AU - Mori, M. AU - Namba, M. PY - 1989 DA - 1989// TI - Two human myeloma cell lines, amylase-producing KMS-12-PE and amylase-non-producing KMS-12-BM, were established from a patient, having the same chromosome marker, t(11;14)(q13;q32) JO - Br J Haematol VL - 73 UR - https://doi.org/10.1111/j.1365-2141.1989.tb00252.x DO - 10.1111/j.1365-2141.1989.tb00252.x ID - Ohtsuki1989 ER - TY - JOUR AU - Ikeyama, S. AU - Nakagawa, S. AU - Arakawa, M. AU - Sugino, H. AU - Kakinuma, A. PY - 1986 DA - 1986// TI - Purification and characterization of IgE produced by human myeloma cell line, U266 JO - Mol Immunol VL - 23 UR - https://doi.org/10.1016/0161-5890(86)90038-6 DO - 10.1016/0161-5890(86)90038-6 ID - Ikeyama1986 ER - TY - JOUR AU - Matsuoka, Y. AU - Moore, G. E. AU - Yagi, Y. AU - Pressman, D. PY - 1967 DA - 1967// TI - Production of free light chains of immunoglobulin by a hematopoietic cell line derived from a patient with multiple myeloma JO - Proc Soc Exp Biol Med VL - 125 UR - https://doi.org/10.3181/00379727-125-32327 DO - 10.3181/00379727-125-32327 ID - Matsuoka1967 ER - TY - JOUR AU - Togawa, A. AU - Inoue, N. AU - Miyamoto, K. AU - Hyodo, H. AU - Namba, M. PY - 1982 DA - 1982// TI - Establishment and characterization of a human myeloma cell line (KMM-1) JO - Int J Cancer VL - 29 UR - https://doi.org/10.1002/ijc.2910290502 DO - 10.1002/ijc.2910290502 ID - Togawa1982 ER - TY - JOUR AU - Hata, H. AU - Matsuzaki, H. AU - Sonoki, T. AU - Takemoto, S. AU - Kuribayashi, N. AU - Nagasaki, A. PY - 1994 DA - 1994// TI - Establishment of a CD45-positive immature plasma cell line from an aggressive multiple myeloma with high serum lactate dehydrogenase JO - Leukemia VL - 8 ID - Hata1994 ER - TY - JOUR AU - Livak, K. J. AU - Schmittgen, T. D. PY - 2001 DA - 2001// TI - Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C(T)) Method JO - Methods VL - 25 UR - https://doi.org/10.1006/meth.2001.1262 DO - 10.1006/meth.2001.1262 ID - Livak2001 ER -