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Figure 1 | Experimental Hematology & Oncology

Figure 1

From: The effect of caffeine on cisplatin-induced apoptosis of lung cancer cells

Figure 1

Cisplatin-induced caspase-3 activation in both HTB182 and CRL5985 lung cancer cells. The lung cancer cells were first treated with caffeine (2 mM) for 24 hours and then with cisplatin (10 μM) for 36 hours before caspase-3 activity was measured. The caspase-3 activity was determined using the Ac-DEVD-AMC as a substrate and measured as nmol AMC/min/mg protein. The p value <0.01 was considered statistically significant in this study (*p value < 0.01; **p value < 0.001).

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