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Table 2 General Linear Model (Multivariate analysis)

From: Activation of Akt at T308 and S473 in alcohol, tobacco and HPV-induced HNSCC: is there evidence to support a prognostic or diagnostic role?

Independent variables

F

P

Corrected model

4.06

<0.001

Smoking

5.30

0.027

Alcohol

10.56

<0.001

Nodal status

1.31

0.260

Age

4.98

0.031

Smoking * Alcohol

3.20

0.052

Smoking * Nodal status

4.12

0.049

Smoking * Age

0.01

0.919

Alcohol * Nodal status

3.56

0.038

Alcohol * Age

5.31

0.009

Nodal status * Age

2.80

0.102

Smoking * Alcohol * Nodal status

0.17

0.682

Smoking * Alcohol * Age

0.08

0.774

Smoking * Nodal status * Age

6.00

0.019

Alcohol * Nodal status * Age

5.73

0.022

R2 = 0.652

  1. Note: After adjusting Smoking, Alcohol, Nodal Status and Age, this model accounts for 65.2% of the total variations in pAkt T308 level. R2 = Coefficient of determination, F = F-statistics.
  2. Dependent variable: pAkt T308 score.