| | |
Akt T308 phosphorylation status
|
Akt S473 phosphorylation status
|
|---|
|
n
|
High
|
Medium
|
Low
|
p
|
Medium
|
Low
|
None
|
p
|
|---|
|
(n = 40)
|
(n = 8)
|
(n = 10)
|
(n = 5)
|
(n = 30)
|
(n = 23)
|
|---|
|
%
|
%
|
%
|
%
|
%
|
%
|
|---|
|
Gender
| | | | |
0.109
| | | |
0.737
|
|
Male
|
33
|
62
|
63
|
30
|
60
|
50
|
65
|
|
Female
|
25
|
38
|
37
|
70
|
40
|
50
|
35
|
|
Age
| | | | |
0.233
| | | |
0.376
|
|
<65 years
|
30
|
50
|
50
|
60
|
80
|
43
|
57
|
|
≥65 years
|
28
|
50
|
50
|
40
|
20
|
57
|
43
|
|
Location
| | | | |
0.217
| | | |
0.094
|
|
FOM
|
10
|
15
|
25
|
20
|
20
|
17
|
17
|
|
RMT
|
8
|
10
|
13
|
30
|
0
|
10
|
22
|
|
SP
|
5
|
10
|
0
|
10
|
40
|
10
|
0
|
|
Tong
|
27
|
53
|
50
|
20
|
20
|
47
|
53
|
|
Alv
|
4
|
5
|
0
|
20
|
0
|
10
|
4
|
|
Other
|
4
|
7
|
12
|
0
|
20
|
6
|
4
|
|
Tumor size
| | | | |
0.173
| | | |
0.213
|
|
T1-T2
|
43
|
70
|
25
|
90
|
60
|
73
|
78
|
|
T3-T4
|
15
|
30
|
75
|
10
|
40
|
27
|
22
|
|
Grade
| | | | |
0.523
| | | |
0.788
|
|
I
|
5
|
8
|
12
|
10
| |
0
|
7
|
13
|
|
II
|
39
|
65
|
75
|
70
| |
80
|
66
|
65
|
|
III
|
14
|
27
|
13
|
20
| |
20
|
27
|
22
|
|
Lymph node metastasis
| | | | |
0.018
| | | |
0.327
|
|
Positive
|
27
|
58
|
12
|
30
|
40
|
50
|
43
|
|
Negative
|
31
|
42
|
88
|
70
|
60
|
50
|
57
|
|
HPV status
| | | | |
0.028
| | | |
0.301
|
|
Positive
|
29
|
40
|
63
|
80
|
40
|
43
|
61
|
|
Negative
|
29
|
60
|
37
|
20
|
60
|
57
|
39
|
|
Smoking
| | | | |
0.022
| | | |
0.449
|
|
Yes
|
42
|
82
|
50
|
50
|
80
|
70
|
74
|
|
No
|
16
|
18
|
50
|
50
|
20
|
30
|
26
|
|
Alcohol
| | | | |
0.027
| | | |
0.968
|
|
Non-drinker
|
7
|
10
|
0
|
30
|
0
|
17
|
9
|
|
Medium drinker
|
21
|
27
|
62
|
40
|
40
|
33
|
39
|
|
Heavy drinker
|
30
|
63
|
38
|
30
|
60
|
50
|
52
|
- Note: The General linear model was used for hypothesis testing of the relationship between different variables and pAkt. The P value was obtained from univariable analysis. Percentages represent the column percentages within variable so that the balance between the pAkt groups could be assessed. Abbreviations: FOM Floor of the mouth, RMT Retromolar trigone, SP Soft palate, Tong Tongue, Alv Alveolus.
