Figure 2

Evaluation of a 3 year-old boy with hyperdiploid B-ALL. A. Abnormal male hyperdiploid karyotype with extra copies of chromosomes X, 2, 9, 14. B. FISH analysis detected +9q, +14q and +21q in 96% , 93.7% and 96% of the nuclei examined, respectively. In addition, 12p deletion was observed in 89% of the nuclei examined, suggestive of an underlying complex aneuploid (most likely hyperdiploid) karyotype.