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Table 6 Positive rates of immunohistochemical markers for mesothelioma, cholangiocarcinoma, lung adenocarcinoma and hepatocellular carcinoma

From: Expression and diagnostic values of calretinin and CK5/6 in cholangiocarcinoma

 

Mesothelioma (all subtypes included)

Cholangiocarcinoma

Lung adenocarcinoma

Hepatocellular carcinoma

WT-1

43-93% [11, 12, 14–17]

0%#

0-7% [12, 14, 16]

NA

D2-40

86-100% [12, 18, 19]

3%#

0-33% [12, 18, 19]

NA

Calretinin

92.4-100% [11, 12, 16, 17, 20, 21]

52%#

8-23% [12, 16, 22]

NA

CK5/6

64-100% [11, 12, 15–17, 20]

0-73.3%#, [23]

0-39% [12, 14–16, 23]

NA

Mesothelin

47-100% [14, 16, 17]

33% [7]

38-100% [14, 16, 22]

NA

CK19

NA

89-100#, [3, 24]

NA

2-10.1% [3, 24]

Annexin A1

NA

94.1% [5]

NA

0% [5]

Glypican-3

NA

6-7% [3, 24]

3.6-9.6% [25, 26]

69-87.1% [3, 24–26]

Arginase

NA

0% [24]

0% [26]

94-95% [24, 26]

TTF-1

0% [16]

0-10% [23, 27]

(nuclear) 20-74% [16, 23]

(cytoplasmic) 50-93% [27–29]

HepPar-1

NA

0-7% [23, 24]

8.1% [26]

74-100% [23, 24, 26]

MOC31

8-35% [14, 16]

88.2% [3]

92-100% [14, 16, 17, 30]

34.0% [3]

EMA

79-93% [16, 21]

100% [31, 32]

100% [16]

12.5-23% [31, 32]

BG 8

7% [16]

NA

95-96% [16, 17]

NA

BerEP4

16-18% [16, 21]

100% [23]

74-100% [16, 17]

33% [23]

  1. Note: #indicates this study; Sensitivity reported in some studies [17] is included; NA: No IHC data on the respective marker are identified by searching the Pubmed database.