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Table 1 Immunohistochemical profiles of the cholangiocarcinoma and accompanying normal bile ducts

From: Expression and diagnostic values of calretinin and CK5/6 in cholangiocarcinoma

  

Negative, n (mean%, 95% confidence intervals)

Positive, n (mean%, 95% confidence intervals)

Total, n (%)

P value*

P value#

Calretinin

CC

11 (47.8, 26.8-69.4)

12 (52.2, 30.6-73.2)

23 (100)

<0.001

NA

 

NBD

23 (100, 85.2-100^)

0 (0)

23 (100)

  

WT1

CC

23 (100, 85.2-100^)

0 (0)

23 (100)

0.312

1

 

NBD

22 (95.6, 78.1-99.9)

1 (4.3, 0.1-21.9)

23 (100)

  

D2-40

CC

29 (96.7, 82.8-99.9)

1 (3.3, 0–17.2)

30 (100)

0.313

1

 

NBD

30 (100, 88.4-100^)

0 (0)

30 (100)

  

CK19

CC

0 (0)

23 (100, 85.2-100^)

23 (100)

0.312

NA

 

NBD

0 (0)

23 (100, 85.2-100^)

23 (100)

  

CK5/6

CC

8 (26.7, 12.3-45.9)

22 (73.3, 54.1 -87.7)

30 (100)

0.002

NA

 

NBD

0 (0)

30 (100, 88.4-100^)

30 (100)

  
  1. Note: CC: Cholangiocarcinoma, NBD: accompanying normal bile duct, NA: not applicable, *comparison between CC and NBD by using Pearson Chi-square test, #comparison between CC and NBD by by using Fischer’s exact test, ^one-sided, 97.5% confidence interval.