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Table 5 Multivariate analysis in the validation cohort excluding high EVI1 cases

From: A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC

Variable

p-value

HR

95% CI

BAALC-low

0.035

1.56

1.03–2.54

CEBPA-dm

0.047

0.35

0.12–0.98

NPM1-ABD

0.36

0.82

0.53–1.26

FLT3-ITD

0.038

1.56

1.02–2.39

age in years

0.012

1.02

1.00–1.04

gender

0.74

1.07

0.72–1.58

White blood Cell Count at diagnosis [×10^9/l]

0.14

1.00

1.00–1.00

Percentage of blast cells in bone marrow

0.2

0.99

0.99–1.00

Platelets at diagnosis [×10^9/l]

0.28

1.00

1.00–1.00

  1. Gene expression, gene mutation and gender variables are binary, while age, WBC, % blast, and platelets are continuous variables.