Table 2 Immunohistochemical and genetic characteristics of the lymphomas
Immunohistochemical analysis | Number (%) | |
|---|---|---|
CD10 expression | Positive | 49 (28.3) |
Negative | 124 (71.7) | |
BCL6 expression | Positive | 59 (34.1) |
Negative | 114 (65.9) | |
MUM1 expression | Positive | 44 (25.4) |
Negative | 129 (74.6) | |
GCB/non-GCB phenotype | GCB | 67 (38.7) |
non-GCB | 106 (61.3) | |
Fibronectin expression | High | 77 (44.5) |
Low | 96 (55.5) | |
SPARC expression | High | 125 (72.3) |
Low | 48 (27.7) | |
CD5 expression | Positive (>20%) | 6 (3.5) |
Negative (<20%) | 167 (96.5) | |
FISH analysis | ||
Number of translocations | 0 | 116 (67.1) |
1 | 53 (30.6) | |
2 | 4 (2.3) | |
FISH for BCL2 | translocation | 23 (13.3) |
no translocation | 131 (75.7) | |
not evaluable | 19 (11) | |
FISH for BCL6 | translocation | 31 (17.9) |
no translocation | 55 (31.8) | |
not evaluable | 87 (50.3) | |
FISH for MYC | translocation | 6 (3.5) |
no translocation | 117 (67.6) | |
not evaluable | 50 (28.9) |