Table 1 OPTC gene expression (RT-PCR) in isolated tumor cells from patients with various types of hematological malignancies and normal leukocyte subsets of healthy control donors
Cell source | No. of positive cases/total no. |
|---|---|
Chronic lymphocytic leukemia (PBMC) | 90/90 |
Mantle cell lymphoma (PBMC) | 2/8 |
Pre B-ALL (PBMC) | 0/1 |
Chronic myelogenous leukemia (PBMC) | 0/7 |
Acute myelogenous leukemia (PBMC) | 0/7 |
Prolymphocytic leukemia (B and T cell types) (PBMC) | 0/3 |
Hairy cell leukemia (PBMC) | 0/2 |
Lymphoplasmacytoid lymphoma (PBMC) | 0/2 |
Multiple myeloma (BMMC) | 0/6 |
Follicular lymphoma (PBMC*) | 0/2 |
Normal healthy PBMC (lymphocytes and monocytes) | 0/20 |
Normal blood T cells** | 0/3 |
Normal blood B cells*** | 0/3 |