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Figure 2 | Experimental Hematology & Oncology

Figure 2

From: Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells

Figure 2

Quantitative OPTC gene expression (q- PCR) in PBMC of CLL patients (non-progressive/progressive) and healthy controls. A The relative expression of OPTC was significantly higher in CLL patients (n = 30) compared to healthy control donors (n = 12) (p < 0,0001). B The relative expression of OPTC was higher in progressive (n = 16) and non-progressive (n = 14) patients compared to healthy donors (p < 0,0001). There was no significant difference in OPTC expression between non-progressive and progressive CLL. Relative expression of OPTC was calculated using the ΔCt method and GAPDH as reference gene.

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