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Table 3 Summary of clinical courses

From: Clinicopathological analysis of primary adrenal diffuse large B-cell lymphoma: effectiveness of rituximab-containing chemotherapy including central nervous system prophylaxis

Case

Treatment

Response to treatment

Overall survival duration (months)

Relapse

Outcome

Cause of death

 1

R-CHOP ×5

PR

45.0

No

Dead

Cholangiocarcinoma

(75% dose)

 2

R-CHOP ×6

PR

7.9

No

Dead

Pneumonia

IT*

 3

R-CHOP ×2

NA

4.0

−

Dead

Exacerbation of pulmonary fibrosis

(70% dose)

 4

R-MPV ×4

CR

40.1

No

Alive

−

IT*

HD-Ara-C ×2

WBRT

 5

R-CHOP ×6

CR

28.0

No

Alive

−

HD-MTX ×2

IT*

 6

R-CHOP ×8

CR

24.8

No

Alive

−

IT*

 7

R-COP ×1

NA

2.6

−

Dead

Pneumonia

(60% dose)

  1. *IT represents prophylactic administration of methotrexate and/or cytarabine.
  2. CR complete response, CRu unconfirmed complete response, HD-Ara-C high-dose cytarabine, HD-MTX high-dose methotrexate, IT intrathecal themotherapy, NA not assessable, R-CHOP rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone, R-COP rituximab, cyclophosphamide, vincristine, and prednisolone, R-MPV rituximab, high-dose methotrexate, procarbazine, and vincristine, WBRT Whole-brain radiotherapy.