Table 3 Expression, immune response, clinical correlation and function of ENOA in cancer
From: Three are better than one: plasminogen receptors as cancer theranostic targets
| Cancer Tissue | Expression | Immune response | Clinical correlation | Function |
|---|---|---|---|---|
| Brain | mRNA [152] | |||
| Bone | protein [170] | Prognosis [170] | ||
| Breast | mRNA, protein [164, 167, 177] | Ab [178, 179] | Prognosis, Survival [167, 178] | Chemoresistance, Metastasis [167, 177, 178] |
| Colon | mRNA, protein [152, 158, 168] | |||
| Gastric | mRNA, protein [152, 162, 169] | T cells [180] | ||
| Head and neck | mRNA, protein [155, 166, 171] | Ab [119, 120] | Prognosis [166] | Metastasis [166] |
| Hematopoietic system | protein [160] | Ab [181] | ||
| Liver | mRNA, protein [130, 152, 156, 165] | Prognosis [156, 165] | Growth, Metastasis [156] | |
| Lung | mRNA, protein [152, 159, 172, 174, 182] | Ab [159, 172, 178, 183, 184] | Prognosis, Survival [172, 174, 178] | |
| Ovary | mRNA, protein [152, 153] | |||
| Pancreas | mRNA, protein [152, 154, 161, 163] | Ab and T cells [154, 185, 186] | Survival [185] | |
| Prostate | mRNA, protein [152, 187] | |||
| Skin | mRNA [173] | Ab [173, 188] |