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Figure 4 | Experimental Hematology & Oncology

Figure 4

From: “T-cell prolymphocytic leukemia (T-PLL), a heterogeneous disease exemplified by two cases and the important role of cytogenetics: a multidisciplinary approach”

Figure 4

A: FISH dual-color break apart probe for the C-MYC gene showing three intact copies B: FISH dual-color break apart probe for T-cell receptor alpha-delta showing a split signal suggesting a rearrangement of TCRA/D. C: FISH showing multiple copies the C-MYC gene (red color). D: FISH dual-color break apart probe for T-cell receptor alpha-delta showing a split signal suggesting a rearrangement of TCRA/D in 90% of the cells E: 27% of these abnormal cells also showed a deletion of the 3′ TRCA/D.

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