Table 3 Studies on clinical significance of E2F1 expression in NSCLC
From: Clinical significance of E2F1 protein expression in non-small cell lung cancer
Study/year1 | Patient number | Adenocarcinoma/SCC | Assay used | Incidence of E2F1 overexpression | Survival difference |
|---|---|---|---|---|---|
Volm/1998 | 96 | 0/96 | IHC | 24% | No |
Gorgoulis/2002 | 77 | 37/37 | IHC | 49% | Yes |
Huang/2007 | 127 | 63/58 | Quantitative RT-PCR | 40% | Yes |
Hung/2012 | 56 | 33/20 | Western blot | 38% | No |