Table 1 Characteristics of 56 patients with non-small cell lung cancer and the relationship between E2F1 protein expression and clinicopathological variables
From: Clinical significance of E2F1 protein expression in non-small cell lung cancer
Variables | Total (n = 56) | E2F1 protein expression | ||
|---|---|---|---|---|
Low (n = 35) | High (n = 21) | P value | ||
Age at operation, years | 65.9 ± 11.1 | 66.8 ± 10.0 | 64.6 ± 12.8 | NS |
Gender | ||||
Male | 41 (73.2) | 27 (77.1) | 14 (66.7) | NS |
Female | 15 (26.8) | 8 (22.9) | 7 (33.3) | |
Smoking index, pack-years | 25.1 ± 32.0 | 29.6 ± 36.1 | 17.9 ± 23.1 | NS |
Tumor size, cm | 4.0 ± 1.6 | 4.0 ± 1.7 | 3.8 ± 1.5 | NS |
Histological type | ||||
Squamous cell carcinoma | 20 (35.7) | 14 (40.0) | 6 (28.6) | NS |
Adenocarcinoma | 33 (58.9) | 20 (57.1) | 13 (61.9) | |
Others | 3 (5.4) | 1 (2.9) | 2 (9.5) | |
T descriptor | ||||
T1 | 7 (12.5) | 3 (8.6) | 4 (19.0) | NS |
T2 | 38 (67.9) | 25 (71.4) | 13 (61.9) | |
T3 | 4 (7.1) | 1 (2.9) | 3 (14.3) | |
T4 | 7 (12.5) | 6 (17.1) | 1 (4.8) | |
N descriptor | ||||
N0 | 33 (58.9) | 20 (57.1) | 10 (61.9) | NS |
N1 | 10 (17.9) | 8 (22.9) | 4 (9.5) | |
N2 | 13 (23.2) | 7 (20.0) | 7 (28.6) | |
Stage | ||||
I | 26 (46.4) | 16 (45.7) | 10 (47.6) | NS |
II | 10 (17.9) | 6 (17.1) | 4 (19.0) | |
III | 20 (35.7) | 13 (37.2) | 7 (33.4) | |
Angiolymphatic invasion | ||||
Absent | 38 (67.9) | 23 (67.6) | 15 (75.0) | NS |
Present | 16 (28.5) | 11 (32.4) | 5 (25.0) | |
Unknown | 2 (3.6) | |||
Histological grade | ||||
Well differentiated | 4 (7.1) | 3 (8.6) | 1 (5.3) | NS |
Moderately differentiated | 36 (64.3) | 23 (65.7) | 13 (68.4) | |
Poorly differentiated | 14 (25.0) | 9 (25.7) | 5 (26.3) | |
Unknown | 2 (3.6) | |||