Skip to main content

Table 1 Characteristics of 56 patients with non-small cell lung cancer and the relationship between E2F1 protein expression and clinicopathological variables

From: Clinical significance of E2F1 protein expression in non-small cell lung cancer

Variables Total (n = 56) E2F1 protein expression
   Low (n = 35) High (n = 21)  P  value
Age at operation, years 65.9 ± 11.1 66.8 ± 10.0 64.6 ± 12.8 NS
Gender     
  Male 41 (73.2) 27 (77.1) 14 (66.7) NS
  Female 15 (26.8) 8 (22.9) 7 (33.3)  
Smoking index, pack-years 25.1 ± 32.0 29.6 ± 36.1 17.9 ± 23.1 NS
Tumor size, cm 4.0 ± 1.6 4.0 ± 1.7 3.8 ± 1.5 NS
Histological type     
  Squamous cell carcinoma 20 (35.7) 14 (40.0) 6 (28.6) NS
  Adenocarcinoma 33 (58.9) 20 (57.1) 13 (61.9)  
  Others 3 (5.4) 1 (2.9) 2 (9.5)  
T descriptor     
  T1 7 (12.5) 3 (8.6) 4 (19.0) NS
  T2 38 (67.9) 25 (71.4) 13 (61.9)  
  T3 4 (7.1) 1 (2.9) 3 (14.3)  
  T4 7 (12.5) 6 (17.1) 1 (4.8)  
N descriptor     
  N0 33 (58.9) 20 (57.1) 10 (61.9) NS
  N1 10 (17.9) 8 (22.9) 4 (9.5)  
  N2 13 (23.2) 7 (20.0) 7 (28.6)  
Stage     
  I 26 (46.4) 16 (45.7) 10 (47.6) NS
  II 10 (17.9) 6 (17.1) 4 (19.0)  
  III 20 (35.7) 13 (37.2) 7 (33.4)  
Angiolymphatic invasion     
  Absent 38 (67.9) 23 (67.6) 15 (75.0) NS
  Present 16 (28.5) 11 (32.4) 5 (25.0)  
  Unknown 2 (3.6)    
Histological grade     
  Well differentiated 4 (7.1) 3 (8.6) 1 (5.3) NS
  Moderately differentiated 36 (64.3) 23 (65.7) 13 (68.4)  
  Poorly differentiated 14 (25.0) 9 (25.7) 5 (26.3)  
  Unknown 2 (3.6)    
  1. NS not significant.
  2. Continuous variables are expressed as mean ± SD; categorical variables are expressed as N (%).