Figure 5From: Childhood B-acute lymphoblastic leukemia: a genetic update Evaluation of a 7Â year-old boy with B-ALL. A. Abnormal male karyotype with a deletion of 11q and trisomy 21. B. FISH analysis demonstrated an abnormal signal pattern consistent with ETV6-RUNX1 (TEL-AML1) fusion, indicative of t(12;21) translocation, as well as +21q and 11q- (MLL deletion).Back to article page